Carbon monoxide and its donors - Chemical and biological properties

Adach, Weronika; Błaszczyk, Mateusz; Olas, Beata

doi:10.1016/j.cbi.2020.108973

Cited by 45 publications

(17 citation statements)

References 24 publications

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“…On the other hand, Bernardini et al ( 2020 ) studied the association between environmental pollutants (CO, NO 2 , O 3 , and PM) and COVID-19 in Italy and found a significant positive correlation between them. Likewise, other researchers such as Adach et al ( 2020 ), Ha ( 2020 ), and Zhu et al ( 2020 ) also observed similar findings. This evidence supports our study and suggests that COVID-19 might spread through environmental pollutants.…”

Section: Resultssupporting

confidence: 71%

Fluctuations in environmental pollutants and air quality during the lockdown in the USA and China: two sides of COVID-19 pandemic

Shakoor

Chen

Farooq

et al. 2020

Air Qual Atmos Health

115

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The World Health Organization declared the outbreak of the novel coronavirus (COVID-19) as a pandemic on March 11, 2020. Due to the global threat, many countries impose immediate lockdown. The impact of lockdown on the environmental pollutants and climate indicators gained considerable attention in the literature. This study aims to describe the variations in the environmental pollutants (CO, NO 2 , SO 2 , PM 2.5 and PM 10) with and without the lockdown period in the majorly hit states and provinces of the USA and China, respectively. Data during the first quarter year of 2019 and 2020 (lockdown period) was used in this study. Moreover, the effect of these pollutants on the pandemic spread was also studied. The results illustrated that the overall concentrations of CO, NO 2 and PM 2.5 were decreased by 19.28%, 36.7% and 1.10%, respectively, while PM 10 and SO 2 were increased by 27.81% and 3.81% respectively in five selected states of the USA during the lockdown period. However, in the case of chosen provinces of China, overall, the concentrations of all selected pollutants, i.e., CO, NO 2 , SO 2 , PM 2.5 and PM 10 , were reduced by 26.53%, 38.98%, 18.36%, 17.78% and 37.85%, respectively. The COVID-19 reported cases and deaths were significantly correlated with NO 2 , PM 2.5 and PM 10 in both China and the USA. The findings of this study concluded that the limited anthropogenic activities in the lockdown situation due to this novel pandemic disease result in a significant improvement of air quality by reducing the concentrations of environmental pollutants. As the trend goes on, the reduction of most pollutant concentrations is expected as long as partial or complete lockdown goes on.

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Section: Resultssupporting

confidence: 71%

Fluctuations in environmental pollutants and air quality during the lockdown in the USA and China: two sides of COVID-19 pandemic

Shakoor

Chen

Farooq

et al. 2020

Air Qual Atmos Health

115

View full text Add to dashboard Cite

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Section: Resultsmentioning

confidence: 54%

“…Bernardini et al (2020) explored the impact of air pollutants, i.e., O 3 , and suggested that a number of patients into the emergency section have direct correlation with air pollutants. Furthermore, Adach et al (2020) and Ha (2020) registered similar findings. Shi et al (2020), based on Chinese provincial data, evaluated the effect of climate indicators and determined that temperature is a key element, which affects the viral outbreak of COVID-19.…”

Section: Methodsmentioning

confidence: 58%

Environmental pollution and COVID-19 outbreak: insights from Germany

Bilal

Bashir

Benghoul

et al. 2020

Air Qual Atmos Health

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The impact of environmental pollutants and climate indicators on the outbreak of COVID-19 has gained considerable attention in the recent literature. However, specific investigation of industrial economies like Germany is not available. This provides us motivation to examine the association between environmental pollutants, climate indicators and the COVID-19 cases, recoveries, and deaths in Germany using daily data from February 24, 2020, to July 02, 2020. The correlation analysis and wavelet transform coherence (WTC) approach are the analytical tools, which are used to explore the association between variables included in the study. Our findings indicate that PM2.5, O 3 , and NO 2 have a significant relationship with the outbreak of COVID-19. In addition, temperature is the only significant climate indicator which has significant correlation with the spread of COVID-19. Finally, PM10, humidity, and environmental quality index have a significant relationship only with the active cases from COVID-19 pandemic. Our findings conclude that Germany's successful response to COVID-19 is attributed to environmental legislation and the medical care system, which oversaw significant overhaul after the SARS and MERS outbreaks. The current study implicates that other industrial economies, especially European economies, that are still facing COVID-19 outbreak can follow the German model for pandemic response.

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“…It is estimated that approximately 500 μmol of CO is produced in human beings per day [2] . Most endogenous CO (∼80 %) is bound to hemoglobin with the formation of COHb, while the remaining CO is distributed in tissues, exerting many important physiological functions including vasodilatory, anti‐inflammatory, anti‐apoptotic, anti‐proliferation effects, etc [3–5] . To date, CO has been recognized as the second gaseous signaling molecule (GSM) following the first GSM of nitric oxide (NO) [6]…”

Section: Introductionmentioning

confidence: 99%

Recent Advances on Carbon Monoxide Releasing Molecules for Antibacterial Applications

Cheng

2021

ChemMedChem

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Carbon monoxide (CO) has been known as an endogenous signaling molecule in addition to an air pollutant. It plays a critical role in many physiological and pathological processes. Therefore, CO has been recognized as a potent therapeutic agent for the treatment of numerous diseases such as cancers, rheumatoid arthritis, and so on. Instead of direct CO inhalation, two main categories of CO‐releasing molecules (CORMs) (i. e., metal carbonyls and nonmetallic CO donors) have been developed to safely and locally deliver CO to target tissues. In this minireview, we summarize the recent achievements of CORMs on antibacterial applications. It appears that the antibacterial activity of CORMs is different from CO gas, which is tightly correlated to not only the types of CORMs applied but also the tested bacterial strains. In some circumstances, the antibacterial mechanisms are debated and need to be clarified. We hope more attention can be paid to this emerging field and new antibacterial agents with a low risk of drug resistance can be developed.

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Carbon monoxide and its donors - Chemical and biological properties

Cited by 45 publications

References 24 publications

Fluctuations in environmental pollutants and air quality during the lockdown in the USA and China: two sides of COVID-19 pandemic

Fluctuations in environmental pollutants and air quality during the lockdown in the USA and China: two sides of COVID-19 pandemic

Environmental pollution and COVID-19 outbreak: insights from Germany

Recent Advances on Carbon Monoxide Releasing Molecules for Antibacterial Applications

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