Carboxyl-functionalized graphene oxide-modified electrode for the electrochemical determination of nonsteroidal anti-inflammatory drug diclofenac

Karuppiah, Chelladurai; Cheemalapati, Srikanth; Chen, Shen‐Ming; Palanisamy, Selvakumar

doi:10.1007/s11581-014-1161-9

Cited by 71 publications

(26 citation statements)

References 47 publications

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“…Carboxyl functionalized GO modified electrode has detected non-steroidal anti-inflammatory drug, diclofenac (DCF) in human urine and serum samples (Karuppiah et al, 2015). This drug is widely used for the treatment of tuberculosis and urinary tract infections and has fewer side effects.…”

Section: Graphene Oxide Biosensors For the Detection Of Different Anamentioning

confidence: 99%

Insight into the biosensing of graphene oxide: Present and future prospects

Sharma

Kanchi

Sabela

et al. 2016

Arabian Journal of Chemistry

109

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Section: Graphene Oxide Biosensors For the Detection Of Different Anamentioning

confidence: 99%

Insight into the biosensing of graphene oxide: Present and future prospects

Sharma

Kanchi

Sabela

et al. 2016

Arabian Journal of Chemistry

109

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“…In view of the prominence of DS in clinical applications, various efforts have been made for the determination of DS, including gas chromatography-mass spectrometry [19,20], liquid chromatography [21][22][23], liquid chromatography-tandem mass spectrometry [24], spectrophotometry [25][26][27][28][29], colorimetry [30], spectrofluorimetry [31], and voltammetry [32][33][34][35][36][37][38][39][40][41][42][43] in biological fluids.…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, electrochemical techniques are simple and versatile due to their advantages such as cheap instrumentation, quick response time, high sensitivity and wide linearity [41,43].…”

Section: Introductionmentioning

confidence: 99%

Gold nanoparticle/multi-walled carbon nanotube modified glassy carbon electrode as a sensitive voltammetric sensor for the determination of diclofenac sodium

Afkhami

Bahiraei

Madrakian

2016

Materials Science and Engineering: C

132

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“…Unfortunately, these methods require frequently a time-consuming initial sample preparation stage due to very low concentrations of DF in water samples.An alternative to the methods described above are electrochemical methods that allow for quick and cheap analysis of real samples. In the research, various types of working electrodes are used, the most popular electrodes are glassy carbon electrodes modified with metal [10], graphene and carbon nanomaterials [1,[11][12][13][14] or organic compounds [15][16][17][18]. In addition, paste electrodes [19] modified with carbon nanomaterials [20-24], silica [25] or organic compounds [26], graphite electrodes [27,28], composite electrodes [27,29], carbon ceramic electrodes [30], boron-doped diamond electrodes [31], and platinum disk electrodes [32,33] are used.…”

mentioning

confidence: 99%

First Electrochemical Sensor (Screen-Printed Carbon Electrode Modified with Carboxyl Functionalized Multiwalled Carbon Nanotubes) for Ultratrace Determination of Diclofenac

et al. 2020

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A simple, sensitive and time-saving differential-pulse adsorptive stripping voltammetric (DPAdSV) procedure using a screen-printed carbon electrode modified with carboxyl functionalized multiwalled carbon nanotubes (SPCE/MWCNTs-COOH) for the determination of diclofenac (DF) is presented. The sensor was characterized using optical profilometry, SEM, and cyclic voltammetry (CV). The use of carboxyl functionalized MWCNTs as a SPCE modifier improved the electron transfer process and the active surface area of sensor. Under optimum conditions, very sensitive results were obtained with a linear range of 0.1-10.0 nmol L −1 and a limit of detection value of 0.028 nmol L −1 . The SPCE/MWCNTs-COOH also exhibited satisfactory repeatability, reproducibility, and selectivity towards potential interferences. Moreover, for the first time, the electrochemical sensor allows determining the real concentrations of DF in environmental water samples without sample pretreatment steps.Keywords: screen-printed carbon electrode modified with carboxyl functionalized multiwalled carbon nanotubes; diclofenac; differential-pulse adsorptive stripping voltammetry; environmental water samples; HPLC with photo-diode array detection Materials 2020, 13, 781 2 of 15 to ground and surface water, causing their pollution. Low water temperatures and short days hinder the process of photolysis and the biodegradation of pharmaceutical preparations, which can cause adverse and unpredictable effects in the ecosystem. The main sources of pollution are factories and production plants, as well as hospitals, health centers, and practically every household. DF is one of the most commonly found ingredients in water, and its concentration is from 3.7 × 10 −11 to 1.4 × 10 −8 mol L −1 [2,3].Although the likelihood of any form of short-term human health risk after DF release into the environment is low, a study links the catastrophic decline of Gyps vulture populations across the Indian subcontinent to DF [4,5]. Generally, NSAIDs such as DF and ibuprofen, for example, have Log Kow values greater than three and may have the capacity to bioaccumulate in the tissues of organisms [6]. DF exhibits acute hepatotoxicity, causes changes in kidneys and gills in rainbow trout (O. mykiss) and exhibits acute toxicity to phytoplankton and zooplankton. Moreover, the possibility of synergetic effects with other pharmaceuticals or chemicals in the aquatic environment increases the environmental risk as well [7].There are many methods in the literature that allow for the determination of DF at various concentration levels. The most popular methods are spectrophotometry (determined DF concentrations: 6.8 × 10 −7 -8.4 × 10 −2 mol L −1 ), spectrofluorimetry (determined DF concentrations: 4.2 × 10 −7 -1.7 × 10 −4 mol L −1 ), calorimetry (determined DF concentrations: 4.6 × 10 −6 -2.7 × 10 −4 mol L −1 ), high-performance thin-layer chromatography (determined DF concentrations: 6.8 × 10 −7 -2.7 × 10 −6 mol L −1 ), and HPLC (determined DF concentrations: 1.7 × 10 −8 -1.4 × 10 −5 mol L −1 )...

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Carboxyl-functionalized graphene oxide-modified electrode for the electrochemical determination of nonsteroidal anti-inflammatory drug diclofenac

Cited by 71 publications

References 47 publications

Insight into the biosensing of graphene oxide: Present and future prospects

Insight into the biosensing of graphene oxide: Present and future prospects

Gold nanoparticle/multi-walled carbon nanotube modified glassy carbon electrode as a sensitive voltammetric sensor for the determination of diclofenac sodium

First Electrochemical Sensor (Screen-Printed Carbon Electrode Modified with Carboxyl Functionalized Multiwalled Carbon Nanotubes) for Ultratrace Determination of Diclofenac

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