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BACKGROUND: Contouring of the nasolacrimal sulcus area is becoming an increasingly popular procedure due to the rapid onset of a pronounced aesthetic result, however, in recent years there has been an increase in the pool of complications both in the early and late post-injection recovery period. At the same time, there are no differentiated approaches to the choice of physiotherapy techniques and their combinations depending on the genetic profile of the patient and the clinical and functional picture of the complication. AIM: to develop and evaluate the use of personalized physiotherapy in patients with complications after the introduction of fillers based on stabilized hyaluronic acid, taking into account their genetic predisposition. MATERIAL AND METHODS: The analyzed data of the study of 47 patients, average age 35.710.2, with a diagnosis of "L57.4 Senile atrophy (lethargy) of the skin", who received late complications (local edema, filler contouring, sensitivity change at the filler injection site) after the introduction of a filler based on stabilized hyaluronic acid in the nasolabial furrow area. All patients underwent genetic testing on the Cosmetology panel before the start of treatment. There were 3 groups that received longidase diadinamophoresis, injection carboxytherapy of the nasolacrimal sulcus area or a combination of the above techniques. RESULTS: When using a combined course of longidase diadinamophoresis and injection carboxytherapy, there was a significant decrease in clinical manifestations in the form of conturation, local edema and neuropathy, the psychoemotional state of patients stabilized. In addition, the therapeutic complex significantly accelerated the biodegradation of the filler and has a restructuring effect on the skin of the nasolacrimal furrow, reducing the thickness of the dermis. increasing the density coefficient of the dermis and accelerating the biodegradation of the superficially injected compared to other study groups. CONCLUSION: The personalized combined use of the method, including a course of longidase diadinamophoresis and injectable carboxytherapy for the correction of complications of contouring of the nasolacrimal sulcus area with fillers based on stabilized hyaluronic acid in the form of local edema, neuropathy and filler contouring, is a highly effective treatment method, which is confirmed by the relief of clinical symptoms, acceleration of biodegradation of the drug and improvement of the quality of life of patients.
BACKGROUND: Contouring of the nasolacrimal sulcus area is becoming an increasingly popular procedure due to the rapid onset of a pronounced aesthetic result, however, in recent years there has been an increase in the pool of complications both in the early and late post-injection recovery period. At the same time, there are no differentiated approaches to the choice of physiotherapy techniques and their combinations depending on the genetic profile of the patient and the clinical and functional picture of the complication. AIM: to develop and evaluate the use of personalized physiotherapy in patients with complications after the introduction of fillers based on stabilized hyaluronic acid, taking into account their genetic predisposition. MATERIAL AND METHODS: The analyzed data of the study of 47 patients, average age 35.710.2, with a diagnosis of "L57.4 Senile atrophy (lethargy) of the skin", who received late complications (local edema, filler contouring, sensitivity change at the filler injection site) after the introduction of a filler based on stabilized hyaluronic acid in the nasolabial furrow area. All patients underwent genetic testing on the Cosmetology panel before the start of treatment. There were 3 groups that received longidase diadinamophoresis, injection carboxytherapy of the nasolacrimal sulcus area or a combination of the above techniques. RESULTS: When using a combined course of longidase diadinamophoresis and injection carboxytherapy, there was a significant decrease in clinical manifestations in the form of conturation, local edema and neuropathy, the psychoemotional state of patients stabilized. In addition, the therapeutic complex significantly accelerated the biodegradation of the filler and has a restructuring effect on the skin of the nasolacrimal furrow, reducing the thickness of the dermis. increasing the density coefficient of the dermis and accelerating the biodegradation of the superficially injected compared to other study groups. CONCLUSION: The personalized combined use of the method, including a course of longidase diadinamophoresis and injectable carboxytherapy for the correction of complications of contouring of the nasolacrimal sulcus area with fillers based on stabilized hyaluronic acid in the form of local edema, neuropathy and filler contouring, is a highly effective treatment method, which is confirmed by the relief of clinical symptoms, acceleration of biodegradation of the drug and improvement of the quality of life of patients.
is a chronic autoimmune disease characterized by changes in the growth and differentiation of the epidermis. 2-5 % of the population of the planet have psoriasis, and it is 30 % in the structure of skin diseases. The multifactorial concept of the pathological process in psoriasis determines a wide range of pharmacotherapy of this disease. Modern antipsoriatic agents are not effective enough and have a variety of side effects.Aim. To summarize the existing scientific literature data conserning the possibility of treating psoriasis with carboxytherapy.Results and discussion. Carboxytherapy is an important part of the treatment and rehabilitation of patients with psoriasis. The antipsoriatic effect of carboxytherapy is realized through the local and resorptive effect of CO 2 : antiproliferative, antiinflammatory, antioxidant, antimicrobial, antihypertrophic, reparative and analgesic. Carboxytherapy in psoriasis promotes tissue detoxification, improves immunity, improves tissue trophism, and eliminates venous-interstitial lymphatic stagnation due to hemodynamic, tissue, and biochemical mechanisms of action of СО 2 .Conclusions. Carboxytherapy as an additional alternative to pharmacotherapy has a synergistic effect together with formulary therapy, but at the same time reduces the dosage of approved drugs and their side effects.
The carbon dioxide of the body is the most important natural regulator of respiration, blood circulation, metabolism, electrolyte balance, nervous system excitability, smooth muscle tonus. Carboxytherapy is based on the use of carbon dioxide. It is an effective and safe method of many diseases’ treatment due to its rich pharmacodynamics. Inhalation of CO2 is used in resuscitation and anesthesiology practice. Another area of CO2 application in surgery is intra‑abdominal insufflation for all endoscopic laparoscopic procedures. Carbon dioxide is quickly absorbed by the mucous membrane of the gastrointestinal tract, which causes an increased interest in its use as an insufflation agent for all endoscopic procedures. In addition, CO2 has antispasmodic, analgesic, anti‑inflammatory and antiseptic effects, which is important for these diagnostic measures. CO2 insufflation during a colonoscopy causes less post‑procedure pain and distension of the intestine without significant changes in pCO2 compared to air one. An additional mechanism for pain reducing after the CO2 procedure may be the vasodilating effect of CO2 and its spasmolytic action on the wall in the enlarged part of the colon. For the past 50 years, CO2 has been used in cardiothoracic surgery to remove air from the surgical area, which reduces the air embolism probabily during heart surgery. Recently, heated and hydrated CO2 insufflation is used as a method to reduce the infections rate at the surgery site in an open wound. A carbon dioxide laser has physical, biological and surgical properties valuable for the surgeon. Carbon dioxide is also used as an alternative diagnostic contrast agent. Therefore, CO2 due to its antibacterial, antihypoxic, antispasmodic, analgesic, anti‑inflammatory, antioxidant properties and the side effects absence is an important component of therapeutic and diagnostic procedures in surgery, anesthesiology, gynecology, dermatology and other fields of medicine.
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