Carcinogenic and non-carcinogenic health risk assessment of heavy metals in drinking water of Khorramabad, Iran

Mohammadi, Ali Akbar; Zarei, Ahmad; Majidi, Saba; Ghaderpoury, Afshin; Hashempour, Yalda; Saghi, Mohammad Hossein; Alinejad, Abdolazim; Yousefi, Mahmood; Hosseingholizadeh, Nasrin; Ghaderpoori, Mansour

doi:10.1016/j.mex.2019.07.017

Cited by 379 publications

(237 citation statements)

References 41 publications

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“…Referring to the total CR, consisting of CR Pb and CR Cd ( Table 5 ), the acceptable level is 10 −5 [ 33 ]. In this case, it can be seen that only samples SV3 and SV10 were considered tolerable, and the rest were in the tolerability range or intolerable.…”

Section: Resultsmentioning

confidence: 99%

Risk Assessment of Lead and Cadmium in Some Food Supplements Available on the Romanian Market

Mustățea

Ungureanu

Iorga

et al. 2021

Foods

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Across the world, there has been an increase in the consumption of food supplements. This may be due to the perception that these dietary supplements cannot negatively affect the health of consumers in any way. However, dietary supplements may not have the expected effect. In addition, it has been shown that supplements can sometimes be chemically, physically or microbiologically contaminated, if the hygiene conditions and Hazard Analysis Critical Control Points (HACCP) plan are not fully complied with. The aim of this study was to determine the lead and cadmium content of 41 food supplements available on the Romanian market and to assess the risk to consumer health. The graphite furnace atomic absorption spectrometry (GFAAS) technique was used for sample analysis after wet mineralization of the samples. The risk assessment was determined based on Estimated Daily Intake (EDI), Target Hazard Quotient (THQ), and Carcinogenic Risk (CR) calculations. Values obtained for both lead and cadmium fall within the limits imposed by the legislation in force. Small risks associated with the consumption of these food supplements was shown, with a main recommendation being to decrease the recommended daily dose in the case of food supplements.

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Section: Resultsmentioning

confidence: 99%

Risk Assessment of Lead and Cadmium in Some Food Supplements Available on the Romanian Market

Mustățea

Ungureanu

Iorga

et al. 2021

Foods

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“…In this regard, health risk assessment associated with the average daily dose (ADD) was determined using the concentrations of As, Cd, Cr, Cu, Fe, Pb, Mn, Ni, and Zn in the water used for drinking. Heavy metals (As, Cd, Cr, Pb, and Ni) can potentially pose a risk of cancer in humans (57,58). Therefore, prolonged exposure to HMs can lead to many types of cancers.…”

Section: Discussionmentioning

confidence: 99%

Assessment of heavy metals concentration in groundwater and their associated health risks near an industrial area

Lorestani

Merrikhpour²,

Cheraghi

2020

Environ Health Eng Manag

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Background: Heavy metals (HMs) contamination from industrial wastewater is a major environmental problem that has been increasing in the past few years. The purpose of this study was to investigate the current status of HMs contamination in Bu-Ali industrial town, Hamedan, western Iran. Methods: The concentration of 9 serious HMs (arsenic, cadmium, chromium, copper, iron, lead, manganese, nickel, and zinc) in groundwater samples was studied during spring 2017. In order to evaluate water quality for aquaculture and drinking purposes, heavy metal evaluation index (HEI), heavy metal pollution index (HPI), and contamination (Cd) indicator were calculated. Health risk of HMs was also calculated to assess the risk of cancer. Results: The results showed that the mean concentration of the HMs according to the Cd index was as follows: Pb > Ni > Cr > Fe > Cd > As > Cu > Zn > Mn. The mean HEI and HPI values were 89.1 and 815.5, respectively. The results also showed that there was no relationship between the HMs concentration and cancer risk. Conclusion: The concentration of the studied HMs in most samples was higher than the permissible limit for drinking water. The HEI and HPI values in high-risk samples were higher than the permissible limit of drinking water, therefore, there is high risk and limitation for aquatic life, but there is no risk of cancer.

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“…Human-health risk assessment is the process of evaluating the probability of harmful effects on human health on exposure to specified chemical agents for a certain period. The health risk assessment can be classified in terms of carcinogenic and non-carcinogenic health risks and generally is based on the determination of risk level [29,30,31,32]. There are several routes through which humans can be exposed to contaminants.…”

Section: Methodsmentioning

confidence: 99%

Non-Carcinogenic Health Risk Assessment due to Fluoride Exposure from Tea Consumption in Iran Using Monte Carlo Simulation

Karami

Fakhri

Rezania

et al. 2019

IJERPH

Self Cite

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Excessive intake of fluoride can cause adverse health effects. Consumption of tea as a popular drink could be a potential source of fluoride exposure to humans. This research aimed to evaluate the fluoride concentration in tea among the Iranian people using the available data in the literature and to assess the health risk related to the consumption of tea in men, women, and children. The health risk assessment was conducted using the chronic daily intake and hazard quotient according to the approach suggested by the Environmental Protection Agency. The fluoride content in published studies varied noticeably, ranging from 0.13 to 3.27 mg/L. The results revealed that the hazard quotient (HQ) in age groups of women (21–72 years) and children (0–11 years) was within the safe zone (HQ < 1) which showed that there was no potential of non-carcinogenic risk associated with drinking tea in these groups. However, in one case of the men (21–72 years), the HQ > 1 which shows a probable risk of fluorosis. The order of non-carcinogenic health risks in the studied groups was in the order of men > women > children. The results of this can be useful for organizations with the responsibility of human health promotion.

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Carcinogenic and non-carcinogenic health risk assessment of heavy metals in drinking water of Khorramabad, Iran

Abstract: Graphical abstract

Cited by 379 publications

References 41 publications

Risk Assessment of Lead and Cadmium in Some Food Supplements Available on the Romanian Market

Risk Assessment of Lead and Cadmium in Some Food Supplements Available on the Romanian Market

Assessment of heavy metals concentration in groundwater and their associated health risks near an industrial area

Non-Carcinogenic Health Risk Assessment due to Fluoride Exposure from Tea Consumption in Iran Using Monte Carlo Simulation

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