2023
DOI: 10.1111/jgh.16219
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Carcinogenic potential in regenerated mucosa after endoscopic resection of esophageal squamous cell carcinoma

Abstract: Background and AimLittle is known about genetic mutations in the regenerated mucosa (RM) after endoscopic resection (ER) of esophageal carcinoma. Thus, this study investigates the status of genetic variation in RM after ER of esophageal squamous cell carcinoma (ESCC).MethodsThe study cohort included 19 patients with ESCC. We used an esophageal carcinoma panel to identify target sequences for squamous cell carcinoma (SCC), background mucosa (BM), and RM after ER of ESCC. We used OncoKB to check whether each mut… Show more

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