Carcinoma Cuniculatum Originating from Intertriginous Lesions

Melo, Carlos R.; Melo, Ivanir S.

doi:10.1111/j.1365-4362.1991.tb02614.x

Cited by 5 publications

(4 citation statements)

References 8 publications

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“…6 Según Melo (1991) durante la segunda y tercera décadas del siglo XX un nuevo crecimiento exportador contribuyó a consolidar definitivamente las bases para el desarrollo capitalista en el país y para su definitiva incorporación en la economía mundial. El café, cultivado sobre todo por campesinos independientes, había contribuido apoyando una transformación general de la economía del país (p.236)…”

Section: Referenciasunclassified

Del mito a la resignificación del paisaje urbano: La representación literaria de la Atenas Suramericana

Llano¹

2020

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El escrito parte de la preocupación por entender los procesos de configuración del Patrimonio Cultural de la ciudad de Bogotá en relación al uso correcto del lenguaje, en una época de gran versatilidad intelectual conocida en América Latina, como “la Atenas suramericana” . Rastrear el cambio de siglo XIX al XX a propósito de uno de los grandes mitos lingüísticos de América Latina, supone un acercamiento detallado a los procesos de construcción de repertorios lingüísticos, legitimación cultural y revalidación de fuentes primarias que logren aclarar este inacabado proceso de modernización cultural en un país como Colombia.

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Section: Referenciasunclassified

Del mito a la resignificación del paisaje urbano: La representación literaria de la Atenas Suramericana

Llano¹

2020

Preprint

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“…Carcinoma cuniculatum has been described in various sites such as esophagus, 10 jaw, 2 oropharynx, 16 sacrum, 9 oral cavity, 11 nasal cavity and sinuses, 27 buttock, 19 hands, 5 toes, 13 thumb, 4 abdominal wall, 17 and intertriginous areas. 20 They were also reported in association with leprosy, 21,24 pilonidal cysts, necrobiosis lipoidica, 23 and chronic skin ulcers. 12 The nomenclature and morphologic definition of carcinoma cuniculatum used in many of these reports is not uniform.…”

mentioning

confidence: 94%

Carcinoma Cuniculatum: A Distinctive Variant of Penile Squamous Cell Carcinoma

Barreto

Velázquez

Ayala

et al. 2007

American Journal of Surgical Pathology

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We are reporting a peculiar variant of penile squamous cell carcinoma (SCC) characterized by its peculiar deeply penetrating and burrowing pattern of growth. This low grade, verruciform penile neoplasm is similar to the plantar epithelioma cuniculatum originally described by Ayrd in 1954. Clinical and pathologic features of 7 patients are presented. There were 7 partial penectomies and 4 bilateral inguinal node dissections. The mean patient's age was 77 years. Grossly, the tumors were white to gray, exo-endophytic, and papillomatous with a cobblestone or spiky appearance. All cases affected the glans and extended to coronal sulcus and foreskin (average size was 6.3 cm). The hallmark of the lesion was noted on cut surface where there were deep tumoral invaginations forming irregular, narrow, and elongated neoplastic sinus tracts connecting the surface of the neoplasm to deep anatomic structures. The neoplasm invaded through lamina propria and corpus spongiosum and grew along the loose connective tissue of Buck fascia to involve the tunica albuginea and corpora cavernosa (average depth was 32 mm). Deeply invasive keratin filled cysts or crypts, on serial sections, showed to be connected to the surface tumor. Fistulization to the skin was also noted. Microscopically, the lesions corresponded to well-differentiated carcinomas with bulbous front of invasion. There were focal areas of higher histologic grade and more infiltrative and jagged borders in 4 cases. Inguinal nodes were negative in 4 patients in which groin dissection was performed. Carcinoma cuniculatum is a variant of penile SCC with distinctive growth pattern and should be distinguished from other verruciform tumors such as the verrucous, papillary, and warty carcinomas. Unlike most subtypes of penile SCCs and despite the deep invasion, none of the tumors showed groin or systemic dissemination at time of diagnosis.

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“…Light microscopy of hematoxylin and eosin–stained sections is the standard technique to support diagnosis of verrucous carcinoma. 21 Although each lesion exhibits individual variation, the histological pattern is uniform. The tumors display both an exophytic and an endophytic component, often with extension to the subcutaneous level.…”

Section: Introductionmentioning

confidence: 99%