Cardiac abnormalities due to multisystem inflammatory syndrome temporally associated with Covid-19 among children: A systematic review and meta-analysis

Aski, Behzad Haghighi; Anari, Ali Manafi; Choobdar, Farhad Abolhasan; Mahmoudabadi, Ramin Zareh; Sakhaei, Maryam

doi:10.1016/j.ijcha.2021.100764

Cited by 39 publications

(48 citation statements)

References 19 publications

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“…Arrhythmias and conduction abnormalities are frequent with ECG findings occurring in 28–67% of MIS-C patients [ 45 •, 46 , 47 ]. The most common are low QRS amplitude and T-wave abnormalities [ 46 ].…”

Section: Cardiac Findings Of Mis-cmentioning

confidence: 99%

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Cardiac Manifestations of Multisystem Inflammatory Syndrome in Children (MIS-C) Following COVID-19

Campbell

2021

Curr Cardiol Rep

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Purpose of Review To review the spectrum of cardiac manifestations and treatments of multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19). Recent Findings Studies demonstrate that up to 80% of children with MIS-C may have cardiac involvement on a spectrum of severity. Cardiac manifestations include myocarditis, coronary artery aneurysms, conduction abnormalities, and arrhythmias. Current treatments, including inotropic support, immunomodulatory therapy, and anti-coagulation, have been effective at resolving these cardiac findings in the majority of patients. COVID-19 can also cause myocarditis in the acute stage of illness and recent descriptions of COVID-19 vaccine myocarditis have occurred. Summary Cardiac manifestations are common in MIS-C and should be assessed for at presentation and during the clinical course as indicated.

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Section: Cardiac Findings Of Mis-cmentioning

confidence: 99%

“…Cases of severe sinus bradycardia have resolved following anti-inflammatory therapy. Reports on ST changes have been discrepant with some reporting this as a rare finding and others indicating this is a more common finding [ 46 , 47 ]. Tachyarrhythmia has also been noted [ 46 , 52 – 54 ].…”

Section: Cardiac Findings Of Mis-cmentioning

confidence: 99%

Cardiac Manifestations of Multisystem Inflammatory Syndrome in Children (MIS-C) Following COVID-19

Campbell

2021

Curr Cardiol Rep

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“…Also, due to the fact that in previous studies, hemodialysis elderly people have received less attention and studies in this field are few and less attention has been paid to the problems of this sensitive group, while this age group is increasing day by day. It is increasing in our country; therefore, this study was conducted to determine the prevalence of cognitive disorders in the elderly on hemodialysis and to identify the factors affecting it [45].…”

Section: Importance and Necessitymentioning

confidence: 99%

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et al. 2021

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The present study was a cross-sectional investigation carried out on elderly patients under chronic hemodialysis who referred to Firoozabadi Hospital during 2019-2020. The study population was 80 patients ≥ 60 years. The patients' cognitive status was determined using MMSE and MOCA tools. The mean age of the candidate patients was 71.71 ± 6.28 years old. Cognitive function was assessed by MMSE and MoCA tests and the mean score of the MMSE test was 20.05 ± 3.50 with the highest score being 26 and the lowest score being 12. Based on the results, these patients were divided into three groups with normal cognitive function, mild cognitive impairment, and severe cognitive impairment. According to the results of the MMSE test, 19 patients (23.75%) had a normal cognitive function and 45 patients (56.25%) had impairment.In other words, the older patients, the lower level of education, the longer duration of hemodialysis, and the patients with a history of diabetes were more susceptible to cognitive impairment. Subsequently, there was a positive correlation between the levels of BUN, creatinine, uric acid, and PTH, which means that the higher level of these variables in patients was related to the higher risk of cognitive impairment. The findings of the present investigation revealed that the cognitive function and the studied variables including age, level of education, history of diabetes, hemodialysis duration, BUN, Creatinine, Uric Acid, PTH, Sodium, and Kt/V had a significant difference in patients undergoing hemodialysis.

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“…Postoperative ileus (POI) is a recognized complication with a prevalence of up to15%. Indeed, it is a temporary the impairment of gastrointestinal (GI) motility after intraabdominal or non-abdominal surgery, arising from the surgical stress response [1][2][3]. It is usually accompanied by vomiting, nausea, abdominal pain and distension, increased morbidity and mortality, delayed postoperative recovery, extended hospitalization and increased healthcare costs.…”

Section: Introductionmentioning

confidence: 99%

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et al. 2021

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Prolonged postoperative ileus can delay hospital discharge. According to the reports, diet and in particular gummy candy may strengthen bowel movements and hence eliminate ileus. A total of 149 patients within the age range of 7-60 years who underwent laparotomy were randomly divided into the experimental group that were treated with gummy candy and the control group which included 73 patients. The experimental group chewed gummy candy four times a day, 6 hours after operation until the first flatulence. The patients in the both groups were checked for bowel movement and flatulence every two hours and it was recorded precisely. Both groups were also divided into 3 subgroups based on surgical incision. On average, the first recorded bowel sound was 10.78 ± 7.66 hours after the surgery. In addition, the first flatulence was recorded on average 2.51 ± 14.32 hours after the surgery. The mean time of hospitalization in both groups was 104.21±7 57.85 hours. The mean duration between the surgical end time, the first recorded bowel sound and the time to first flatulence was significantly lower in the experimental group compared with the control group.

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Cardiac abnormalities due to multisystem inflammatory syndrome temporally associated with Covid-19 among children: A systematic review and meta-analysis

Cited by 39 publications

References 19 publications

Cardiac Manifestations of Multisystem Inflammatory Syndrome in Children (MIS-C) Following COVID-19

Cardiac Manifestations of Multisystem Inflammatory Syndrome in Children (MIS-C) Following COVID-19

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