Cardiac Intimal Sarcoma with Complete Response to Thoracic Radiotherapy- A Case Report

Aurélia, Alati; Valerie, Le Brun-Ly; Léobon, Sophie; Pommepuy, Isabelle; Romain, Turcat; Helene, Orliac; Pierre, C

doi:10.26502/acmcr.96550220

Cited by 2 publications

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“…No evidence-based management guideline is available for treatment strategies. Data for chemotherapy and radiotherapy use is mixed ( 5 , 7 , 8 ). Novel treatment therapies including those aimed at MDM2 oncogene overexpression are under investigation ( 6 ).…”

Section: Discussionmentioning

confidence: 99%

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An Unusual Cause of Functional Mitral Stenosis

Diamond

VanderLaan

et al. 2021

JACC: Case Reports

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Primary cardiac tumors are rare, with an incidence of <0.1% in postmortem series; sarcomas comprise 75% of these. Cardiac sarcomas may be life-threatening at the time of presentation. We describe a left atrial intimal sarcoma presenting with constitutional symptoms, obstructive shock, and systemic emboli, and treated with proton beam therapy. ( Level of Difficulty: Intermediate. )

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Section: Discussionmentioning

confidence: 99%

“…Novel treatment therapies including those aimed at MDM2 oncogene overexpression are under investigation ( 6 ). Proton beam therapy is an emerging treatment used to maximally spare uninvolved cardiac structures and was used in this case with a goal of improving long-term survival ( 8 ).…”

Section: Discussionmentioning

confidence: 99%

An Unusual Cause of Functional Mitral Stenosis

Diamond

VanderLaan

et al. 2021

JACC: Case Reports

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A Case of Surgical Treatment of Primary Cardiac Intimal Sarcoma in the Left Atrium

Murakami¹,

Minamimura

Baba

et al. 2022

J. J. C. V. S.

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Primary cardiac malignant tumor is rare and is associated with very poor survival. We report a case of a 45-year-old female who presented with dyspnea and general edema due to severe congestive heart failure, in whom an echocardiographic exam showed a large mass in the left atrium, mitral valve regurgitation and tricuspid valve regurgitation and the tumor resection, mitral valve repair and tricuspid annuloplasty were performed under semi-emergency. The pathological diagnosis of the resected tumor was cardiac intimal sarcoma which recurred; the patient needed re-surgery after 1 year and 5 months, and chemotherapy by pazopanib was performed. She died due to widespread metastasis. A relatively long-term survival of two years and 1 month after the initial surgery was achieved.

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Cardiac Intimal Sarcoma with Complete Response to Thoracic Radiotherapy- A Case Report

Cited by 2 publications

References 0 publications

An Unusual Cause of Functional Mitral Stenosis

An Unusual Cause of Functional Mitral Stenosis

A Case of Surgical Treatment of Primary Cardiac Intimal Sarcoma in the Left Atrium

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