2000
DOI: 10.1007/s004240050932
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Cardiac loading conditions modify the ventricular repolarization in conscious dogs with heart failure

Abstract: Changes in myocardial loading conditions influence the ventricular action potential via mechanoelectric feedback, a mechanism impaired in pathology. In vivo the QT interval of the electrocardiogram which reflects the action potential duration allows appropriate determination of its modifications. The effects of changes in cardiac loading conditions (load reduction with trinitrin; volume loading with Plasmion) on regional function and ventricular local electrogram were investigated in conscious dogs before (con… Show more

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