Care before and after Laser Skin Resurfacing. A Survey and Review of the Literature

Abstract

Many options are appropriate, based on data from past studies, for pre- and postresurfacing skin care. Approximately 73% of the results of the survey correlate with information from the literature. Past studies do provide information to help us select interventions that can improve wound healing and the final cosmetic outcome. Further studies involving resurfacing patients may clarify some of the more complex wound care issues, such as oral prophylactic antibiotics, hydroquinone, and topical vitamins C and E.

Tretinoin treatment before carbon-dioxide laser resurfacing: A clinical and biochemical analysis

“…In fact, in a survey of physician members of the American Society for Laser Medicine and Surgery reported in 1998, 80% of respondents recommended a regimen of topical tretinoin before laser resurfacing. 16 However, much of the evidence regarding the potential benefits of pre-CO 2 laser tretinoin therapy is based on extrapolation from earlier animal and human studies regarding the use of this agent before dermabrasion, chemical peeling, and full-thickness wounding of the skin. [10][11][12][13][14]17 The wounds created by ablative laser therapy may differ from those because of these other procedures, and we sought to examine the biochemical and clinical effects of pretreatment with tretinoin before CO 2 laser therapy in photodamaged human skin in vivo.…”

Collagen thermal damage and collagen synthesis after cutaneous laser resurfacing

“…No differences were seen among the different methods of postoperative care [9,10]. Figure 1 shows representative histology from the scanned and short-pulsed laser wounds harvested on the day of resurfacing (A, B) and postoperative day 7 (C, D).…”

“…A porcine model for human skin [10] was used and institutional guidelines regarding animal experimentation were followed. Piglets were anesthetized with halothane during the laser treatment.…”

Ablatif Lazerler

“…Bazı hekimler, işlem bölgesinde kandidiyal enfeksiyon riskini önlemek için işlem sırasında tek doz oral flukanazol tavsiye ederler. İşlemden sonraki ilk 72 saatte ortaya çıkan yüz ödemini engellemek için 3-4 günlük kısa bir oral kortikosteroid kürü uygulanabilir [13][14][15] .…”

“…Reepitelizasyon tipik olarak 6-7 günde gerçekleşmesine rağmen, postoperatif eritem aylarca kalabilir. Dikkatlice seçilmiş ve uyumlu hastalarda etkiler daha yüz güldürücüdür [12][13][14][15] .…”