Caries prevalence and tooth surface distribution in a group of 5-year-old Italian children

Ferro, R; Besostri, A; Olivieri, Armando

doi:10.1007/bf03262665

Cited by 22 publications

(24 citation statements)

References 15 publications

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“…As reported in a previous study 15 , the presence of highly structured and enlarged EPS-enmeshed micro-colonies could retain produced acids more effectively than those from non-structured bacterial accumulation. In general, our data may explain the results of previous epidemiological studies that show the incidence of dental caries on occlusal surfaces of mandibular posterior teeth is higher than of maxillary posterior teeth 7 , 16 . Collectively, despite the same area of exposure to S. mutans , biofilm accumulation, CFU counts, and EPS amount on substratum surfaces (sHA discs) were highest in the upward direction, followed by those in the vertical and downward directions, which might be related to gravity.…”

Section: Discussionsupporting

confidence: 85%

Difference in virulence and composition of a cariogenic biofilm according to substratum direction

Dang

Jung

Choi

et al. 2018

Sci Rep

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The aim of this study was to investigate the difference in composition and virulence of Streptococcus mutans biofilms according to substratum direction. S. mutans biofilms (46-h-old) were formed on three different saliva-coated hydroxyapatite (sHA) disc direction groups: downward (discs placed in the direction of gravity), vertical (discs placed parallel to gravity direction), and upward (discs placed opposite to gravity). The 46-h-old biofilms on sHA discs in the upward direction showed the highest biofilm accumulation, colony forming unit (CFU) count, and extracellular polysaccharide (EPS) amount, followed by those in the vertical and downward directions. In the confocal laser scanning microscopy (CLSM) study, the biofilms in the upward direction also showed the highest bacterial count (live or dead cells) and EPS biovolume. Scanning electron microscopy (SEM) analysis confirmed the microbiological and biochemical results. In addition, biofilm density and acid production were higher in the upward direction than those in the other directions. Our findings suggest that substratum direction, which might be related to gravity, strongly influences the formation and virulence of cariogenic biofilms and subsequent initiation of dental caries. Collectively, the differences in the formation and virulence of cariogenic biofilms are related to the direction of tooth surface (occlusal surfaces of mandibular teeth > proximal surfaces > occlusal surfaces of maxillary teeth).

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Section: Discussionsupporting

confidence: 85%

Difference in virulence and composition of a cariogenic biofilm according to substratum direction

Dang

Jung

Choi

et al. 2018

Sci Rep

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“…With this, dental plaque tends to accumulate in hard-to-clean areas, such as pits and fissures on occlusal surfaces, and tight contact areas on proximal surfaces. This makes the occlusal surfaces of the posterior teeth and proximal surfaces vulnerable sites for dental caries (König 1963;Ferro et al 2009). Correspondingly, the results of the present study support the use of NaF with fTCP for the control of dentine caries on the buccal/lingual surfaces of the anterior teeth.…”

Section: Discussionsupporting

confidence: 82%

Randomized Clinical Trial on Sodium Fluoride with Tricalcium Phosphate

et al. 2020

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This 24-mo randomized controlled trial was based on a double-blind parallel design, and it compared the effectiveness of 2 fluoride application protocols in arresting dentine caries in primary teeth. Three-year-old children with active dentine caries were recruited and randomly allocated to 2 treatment groups. Children in group A received a semiannual application of a 25% silver nitrate (AgNO3) solution followed by a commercially available varnish with 5% sodium fluoride (NaF) on the carious tooth surfaces. Children in group B received a semiannual application of a 25% AgNO3 solution followed by another commercially available varnish with 5% NaF containing functionalized tricalcium phosphate (fTCP). Carious tooth surfaces that were hard when probing were classified as arrested. Intention-to-treat analysis and a hierarchical generalized linear model were undertaken. A total of 408 children with 1,831 tooth surfaces with active dentine caries were recruited at baseline, and 356 children (87%) with 1,607 tooth surfaces (88%) were assessed after 24 mo. At the 24-mo evaluation, the mean (SD) number of arrested carious tooth surfaces per child were 1.8 (2.2) and 2.6 (3.3) for group A (without fTCP) and group B (with fTCP), respectively ( P = 0.003). The arrest rates at the tooth surface level were 42% for group A and 57% for group B ( P < 0.001). Results of the hierarchical generalized linear model indicated that protocol B (with fTCP) had a higher predicted probability (PP = 0.656) in arresting dentine caries than protocol A (without fTCP; PP = 0.500) when the carious lesions were on buccal/lingual surfaces, were on anterior teeth, had dental plaque coverage, and were in children from low-income families ( P = 0.046). In conclusion, protocol B, which applied a 25% AgNO3 solution followed by a commercially available 5% NaF varnish with fTCP semiannually, is more effective in arresting dentine caries in primary teeth as compared with protocol A, which applied a 25% AgNO3 solution followed by another commercially available 5% NaF varnish without fTCP semiannually (ClinicalTrials.gov NCT03423797).

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“…Earlier studies pointed out that especially primary molars and maxillary incisors are very susceptible 6–9 . Primary molars show the highest attack levels in pits and fissures, and when also the proximal surfaces are involved, the mesial surface of the second and the distal surface of the first molar are most frequently affected 7,10,11 .…”

Section: Introductionmentioning

confidence: 99%

Impact of caries onset on number and distribution of new lesions in preschool children

Leroy¹,

Declerck²

2012

Int J Paed Dentistry

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Caries prevalence and tooth surface distribution in a group of 5-year-old Italian children

Abstract: Caries experience in the primary dentition showed a symmetrical distribution localized on primary molars, most often in their occlusal surface. Caries in anterior teeth was uncommon.

Cited by 22 publications

References 15 publications

Difference in virulence and composition of a cariogenic biofilm according to substratum direction

Difference in virulence and composition of a cariogenic biofilm according to substratum direction

Randomized Clinical Trial on Sodium Fluoride with Tricalcium Phosphate

Impact of caries onset on number and distribution of new lesions in preschool children

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