Cartilage and bone injectable hydrogels: A review of injectability methods and treatment strategies for repair in tissue engineering

Shaygani, Hossein; Mofrad, Yasaman Mozhdehbakhsh; Demneh, Seyed Mohammadhossein Rezaei; Hafezi, Shayesteh; Almasi-Jaf, Aram; Shamloo, Amir

doi:10.1016/j.ijbiomac.2024.136689

International Journal of Biological Macromolecules

2024

DOI: 10.1016/j.ijbiomac.2024.136689

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Cartilage and bone injectable hydrogels: A review of injectability methods and treatment strategies for repair in tissue engineering

Hossein Shaygani,

Yasaman Mozhdehbakhsh Mofrad,

Seyed Mohammadhossein Rezaei Demneh

et al.

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2024

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Characterization of Biopolymer Hydrogels Prepared with Water Exposed to Indirect Plasma Treatment

Król-Kilińska,

Kulig,

Zimoch-Korzycka

et al. 2024

IJMS

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This study aimed to evaluate the influence of indirect-plasma-treated water (IPTW) in the preparation of hydrogels. Three commonly used natural, biodegradable polymers with the ability to form gels were selected: gelatin, carrageenan, and sodium alginate. The pH, gelling temperature, texture profile, swelling degree, and color of hydrogels were evaluated, and the polymers were subjected to Fourier-transform infrared (FTIR) spectroscopy. The morphology of the hydrogels was investigated using Scanning Electron Microscopy (SEM). Additionally, the physiochemical properties of the water media, which were distilled water (DW) and IPTW, were analyzed. The results indicated that the gels prepared using IPTW were characterized by a lower pH, higher hardness and lower gelation temperature. After 48 h of swelling ratio (SR) testing, gelatin and alginate hydrogels made with IPTW were characterized by lower SR, while an inverse relationship was found in the case of SR of carrageenan gels. The FTIR analysis confirmed changes in the water binding ability. The use of IPTW also significantly affected the microstructure of the tested materials. A statistically significant change in the color of IPTW gel samples was also noted. The results showed that IPTW induces physicochemical changes in hydrogels, which can lead to the enhancement of their practical applications.

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Characterization of Biopolymer Hydrogels Prepared with Water Exposed to Indirect Plasma Treatment

Król-Kilińska,

Kulig,

Zimoch-Korzycka

et al. 2024

IJMS

View full text Add to dashboard Cite

show abstract

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Cartilage and bone injectable hydrogels: A review of injectability methods and treatment strategies for repair in tissue engineering

Cited by 1 publication

References 254 publications

Characterization of Biopolymer Hydrogels Prepared with Water Exposed to Indirect Plasma Treatment

Characterization of Biopolymer Hydrogels Prepared with Water Exposed to Indirect Plasma Treatment

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