Case #6: Management of Stage 3 Hallux Limitus Deformity with Acellular Dermal Allomatrix for Resurfacing of the First Metatarsal Head

Visser, Harry John

doi:10.1007/978-3-031-07893-4_6

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…Alternately, the ion alterations and cell polarity changes in the surrounding muscles of some individuals can lead to muscular imbalance and changes in the anatomic position of the rst metatarsal, including its rotation, which are nonetheless classi ed as bunion (52).…”

Section: Summary Of Evidencementioning

confidence: 99%

How might the consideration of cell polarity affect the daily therapeutic practise? A review study.

Ravanbod

2023

Preprint

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Background: In addition to biochemical gradients and transcriptional networks, the behaviour of cells is controlled by endogenous bioelectrical signals resulting from the action of ion channels and pumps. Both biochemical and transcription network modifications can have their impacts through bioelectric modifications, and bioelectric modifications by producing polarity can act as precursor patterns for future genetic evolutions and biochemical modifications. In further details, the proliferation, differentiation, cell shape, and death of stem, progenitor, and somatic cells are governed by instructive messages mediated by variations in resting potential. Cells are regulated not only by their own Vmem (membrane resting potential) but also by the Vmem of their neighbours, establishing networks through electrical synapses known as gap junctions. Changes in the spatial and temporal distribution of Vmem in nonneuronal somatic tissues produce cell polarity which govern pattern development and act as signals that establish the polarity of the body's anatomical axis, and initiate limb regeneration. This article discusses how variations in cell polarity can induce clinical problems and how examining cell polarity might aid in symptom management. Methods: Using Ovid-MEDLINE, Cochrane central, PubMed, Scopus, Web of Science (WOS), and Embase, a comprehensive qualitative literature review was conducted from February 1, 2018, through February 1, 2023. This evaluation includes all types and designs of studies involving the phrases bioelectric, cell polarity, electroceuticals, human, people, diseases, illnesses, and foot and ankle problems, which were connected using the conjunctions "and" and "or." Results: From a total of 1281 publications identified, 27 were chosen. One of this research investigated bioelectric wound healing. 25 studies addressed bioelectric nerve cell growth, whereas one evaluated bioelectricity-induced cellular differentiation in the treatment of arteriopathies. Conclusion: After analysing the data, the author recommends that cell polarity be addressed for the treatment and prevention of most, if not all, foot and ankle problems. This strategy will assist in addressing most of the predisposing factors and healing impediments for a disease, hence enhance healing process and reducing the likelihood of recurrence or parallel conditions. Due to the limits of bioelectricity measurement and the involvement of mechanical and chemical gradients, more studies are required to confirm these results.

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Section: Summary Of Evidencementioning

confidence: 99%

How might the consideration of cell polarity affect the daily therapeutic practise? A review study.

Ravanbod

2023

Preprint

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“…Alternately, ion alterations and cell polarity changes in the surrounding muscles of some individuals can lead to muscular imbalance and changes in the anatomic position of the first metatarsal, including its rotation. These changes are classified as bunion [48].…”

Section: Summary Of Evidencementioning

confidence: 99%

How Might Consideration of Cell Polarity Affect Daily Therapeutic Practices? A Literature Review

Ravanbod

2023

GMJ

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Background: In addition to biochemical gradients and transcriptional networks, cell behaviour is controlled by endogenous bioelectrical signals resulting from the action of ion channels and pumps. Cells are regulated not only by their own membrane resting potential (Vmem) but also by the Vmem of neighbouring cells, establishing networks through electrical synapses known as gap junctions. V mem is the primary factor in producing a polarity that can regulate cell assimilation of various substances. This article aimed to examine how cell polarity can change and how variations in cell polarity may lead to clinical demonstrations.Materials and Methods: Using Cochrane Central, PubMed, Scopus, Web of Science (WOS), and Embase, a comprehensive qualitative literature review was conducted from February 1, 2018, to February 1, 2023, to identify studies addressing bioelectric, cell polarity, and electroceuticals in patients with foot and ankle problems.Results: Out of 1,281 publications, 27 were included. One study investigated bioelectric wound-healing. Twenty-five studies examined bioelectric nerve cell growth, whereas one study evaluated bioelectricity-induced cellular differentiation in the treatment of arteriopathies.Conclusion: The author of this systematic review support addressing the predisposing factors and healing impediments for a disease, thereby enhancing the healing process and reducing the likelihood of recurrence or parallel conditions. This method of treatment has provided a summary of evidence indicating that cell polarity could be addressed for the treatment and prevention of most if not all, foot and ankle problems. However, owing to the limitations of V mem and bioelectricity measurement and the direct or indirect involvement of genetics and chemical gradients, further studies are required to confirm these results.

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Case #6: Management of Stage 3 Hallux Limitus Deformity with Acellular Dermal Allomatrix for Resurfacing of the First Metatarsal Head

Cited by 2 publications

References 9 publications

How might the consideration of cell polarity affect the daily therapeutic practise? A review study.

How might the consideration of cell polarity affect the daily therapeutic practise? A review study.

How Might Consideration of Cell Polarity Affect Daily Therapeutic Practices? A Literature Review

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