Case-Matched Comparison of Vitrectomy, Peripheral Retinal Endolaser, and Endocyclophotocoagulation Versus Standard Care in Neovascular Glaucoma

Marra, Kyle V.; Wagley, Sushant; Omar, Ahmed F.; Kinoshita, Taiga; Kovacs, Kyle D.; Silva, Paolo; Kuperwaser, Mark C.; Arroyo, Jorge G.

doi:10.1097/iae.0000000000000449

Cited by 25 publications

(31 citation statements)

References 24 publications

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“…Marra et al reported a 70% reduction in IOP at postoperative month 12 in a cohort of patients only with neovascular glaucoma (NVG) . However, this NVG cohort had a mean preoperative IOP of 40.7 mmHg, significantly higher than our ECP‐plus cohort's mean preoperative IOP of 27.7 mmHg . Regarding medication reduction following ECP‐plus, we observed a modest effect compared to other studies; our cohort demonstrated a mean decrease of 2.1 medications, while other studies have reported a 2.7 to 2.8 reduction in mean number of medications following ECP‐plus .…”

Section: Discussioncontrasting

confidence: 85%

“…We noted an approximately 50% reduction in IOP from baseline at postoperative months 12 and 24, which is comparable to Tan et al's study reporting an approximately 65% IOP reduction at postoperative month 12 for patients with refractory glaucoma . Marra et al reported a 70% reduction in IOP at postoperative month 12 in a cohort of patients only with neovascular glaucoma (NVG) . However, this NVG cohort had a mean preoperative IOP of 40.7 mmHg, significantly higher than our ECP‐plus cohort's mean preoperative IOP of 27.7 mmHg .…”

Section: Discussionsupporting

confidence: 78%

“…Of note, Tan et al only treated 300° to 330° around the circumference of the ciliary processes, whereas most of our cases received 360° treatment. ECP‐plus treated eyes in the study by Marra et al received 360° treatment and had the following incidence rates: hyphema (11%), retinal detachment (4%), vitreous haemorrhage (0%) and prolonged hypotony (8%) . Neither of the above two studies, nor our study, showed significant visual acuity changes in the ECP‐plus groups at any time point compared to the preoperative value.…”

Section: Discussioncontrasting

confidence: 46%

“…The paucity of longitudinal safety and efficacy data for ECP‐plus has prompted us to examine its purported benefits and possible complications . In addition, no study has yet to directly compare traditional anterior ECP with ECP‐plus.…”

Section: Introductionmentioning

confidence: 99%

“…13 The paucity of longitudinal safety and efficacy data for ECP-plus has prompted us to examine its purported benefits and possible complications. 13,14 In addition, no study has yet to directly compare traditional anterior ECP with ECP-plus. Therefore, we conducted this study to compare the safety and efficacy of anterior ECP with ECP-plus, utilizing data from glaucoma patients treated by the same team of physicians at a single site with 2-year follow-up.…”

Section: Introductionmentioning

confidence: 99%

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Comparison between pars plana and anterior endoscopic cyclophotocoagulation for the treatment of glaucoma

Feinstein

Lee

Amoozgar

et al. 2019

Clinical Exper Ophthalmology

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Importance This is the first study to compare the efficacy and safety of endocyclophotocoagulation (ECP) via pars plana (ECP‐plus) with ECP via limbus (anterior ECP) for treating glaucoma. Background There is no direct comparison of treatment outcomes between ECP‐plus and anterior ECP. Design Retrospective study. Participants Fifty‐four consecutive patients. Methods Fifty‐eight eyes from 54 consecutive patients underwent anterior ECP (33 eyes) or ECP‐plus (25 eyes) with 2‐year follow‐up. Linear mixed model was used to analyse the surgical outcomes. Main Outcome Measures Intraocular Pressure (IOP) was the primary outcome. Secondary outcomes were best‐corrected visual acuity, number of glaucoma medications, complications and success rate. Results Compared to anterior ECP, patients in the ECP‐plus group had lower IOP (estimate of effect size [EES] = −3.7 mmHg, P = 0.023) and used fewer number of glaucoma medications (EES = −1.11, P = 0.003), after adjusting for degrees of treatment, preoperative IOP, and presence of combined ECP and phacoemulsification procedure. Patients with ECP‐plus achieved a higher success rate at 2 years postoperatively (80% vs 33.3%, P < 0.001). The decrease in IOP between the preoperative and last follow‐up visit was greater in the ECP‐plus group compared to the anterior ECP group (14.3 mmHg (52%) vs 5.2 mmHg (24%), P = 0.001). There was no significant difference in complication rates between the two groups (28% vs 33%, P = 0.561). Conclusions and Relevance Anterior ECP and ECP‐plus have a similar safety profile, and ECP‐plus may offer superior IOP control for the management of glaucoma.

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Section: Discussioncontrasting

confidence: 85%

Section: Discussionsupporting

confidence: 78%

Section: Discussioncontrasting

confidence: 46%

Section: Introductionmentioning

confidence: 99%