Case Report: A case of radioactive iodine-refractory thyroid cancer accompanying cervical lymph node metastasis treated with US-guided RFA combined with 125I seed implantation

Abstract

BackgroundLocal control of metastases is critical to improving the life quality of patients with radioactive iodine-refractory (RAIR) thyroid cancer accompanying regional lymph node metastasis.Case reportThe reported patient suffered from RAIR thyroid cancer accompanying poorly controlled cervical lymph node metastasis. The patient’s lesions were controlled through 125I seed implantation combined with ultrasound-guided radio-frequency ablation (US-guided RFA). Such a combination therapy has not been reported to date.ConclusionThis study found US-guided RFA combined with 125I seed implantation to be safe and effective for the control of cervical local metastases in patients with RAIR thyroid cancer.

Ultrasound-guided radiofrequency ablation for the treatment of papillary thyroid carcinoma: a review of the current state and future perspectives

“…For challenging and severe cases, including those with lesions protruding from the skin or rupture, this method offers safe and reliable treatment with high clinical utility. Zhai et al [ 58 ] found that US-guided RFA combined with iodine-125 implantation could safely and effectively control local metastatic tumors, while also improving patients’ quality of life. These findings demonstrate the utility of palliative RFA in the management of recurrent and metastatic PTC.…”