2023
DOI: 10.3389/fimmu.2023.1078838
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Case report: Electrocardiographic changes in pembrolizumab-induced fatal myocarditis

Abstract: Immune checkpoint inhibitor (ICI)-induced myocarditis is rare but fatal. Because of the rapid course of ICI-induced myocarditis, understanding of clinical course is only possible through information from case reports. We report a case of pembrolizumab-induced myocarditis in which we were able to document the course of electrocardiographic changes from onset to death. A 58-year-old woman with stage IV lung adenocarcinoma, who had completed her first cycle of pembrolizumab, carboplatin, and pemetrexed, was admit… Show more

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Cited by 4 publications
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“…26 cases of SARS-CoV-2 infection during ICIs therapy were collected from 19 research centers (Table 1 ), based on the degree of disease progression, ICU admission or intubation, we divided 26 patients into mild (73.1%) [ 34 45 ] and severe cases (26.9%) [ 46 52 ]. Of them, 65.4% were male, and the median age was 62.0 (22–83) years.…”
Section: Clinical Characteristics Of Sars-cov-2 Infection In Cancer P...mentioning
confidence: 99%
“…26 cases of SARS-CoV-2 infection during ICIs therapy were collected from 19 research centers (Table 1 ), based on the degree of disease progression, ICU admission or intubation, we divided 26 patients into mild (73.1%) [ 34 45 ] and severe cases (26.9%) [ 46 52 ]. Of them, 65.4% were male, and the median age was 62.0 (22–83) years.…”
Section: Clinical Characteristics Of Sars-cov-2 Infection In Cancer P...mentioning
confidence: 99%