2021
DOI: 10.3389/fpain.2021.753464
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Case Report: Initial Evidence of Safety and Efficacy of High Definition-Transcranial Direct Current Stimulation in a Patient With Neuropathic Pain and Implanted Spinal Cord Stimulator

Abstract: Neuropathic pain (NP), often treatment-refractory, is one of the most debilitating conditions contributing to suffering and disability worldwide. Recently, non-invasive neuromodulation techniques, particularly repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) have emerged as potential therapeutic alternatives due to their ability to alter cortical excitability of neural circuits. However, the magnetic field induced in rTMS may be unsafe for patients with an … Show more

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“…Although the placement of the anode tDCS was centered on the motor cortex, the size of the electrodes and the standard motor-prefrontal montages entail a current distribution covering a region much more extended than the focalized figure-of-eight rTMS coil, and could render the comparison hazardous [47]. New highdefinition tDCS montages could permit more focalized current distribution around the motor cortex, but their use in neuropathic pain remains anecdotal [48]. Finally, our fMRI analysis was restricted to the activations induced by a motor task.…”
Section: Limitationsmentioning
confidence: 99%
“…Although the placement of the anode tDCS was centered on the motor cortex, the size of the electrodes and the standard motor-prefrontal montages entail a current distribution covering a region much more extended than the focalized figure-of-eight rTMS coil, and could render the comparison hazardous [47]. New highdefinition tDCS montages could permit more focalized current distribution around the motor cortex, but their use in neuropathic pain remains anecdotal [48]. Finally, our fMRI analysis was restricted to the activations induced by a motor task.…”
Section: Limitationsmentioning
confidence: 99%