Case Report. MR Appearance of Pulmonary Metastatic Calcification

Taguchi, Yasushi; Fuyuno, G; Shioya, Sumie; Yanagimachi, Noriharu; Katoh, Hirokazu; Matsuyama, S; Ohta, Yasuyo

doi:10.1097/00004728-199601000-00008

Cited by 20 publications

(17 citation statements)

References 9 publications

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“…Electron beam CT and spiral CT are highly sensitive techniques for detecting coronary artery calcification, and are being used with increasing frequency for screening asymptomatic individuals at risk for the development of coronary artery disease [19]. MRI is relatively insensitive for detecting PC because neither calcium nor air in the lung typically transmits a signal, thereby failing to produce a contrast [20].…”

Section: Discussionmentioning

confidence: 99%

Pulmonary calcification in hemodialysis patients: Correlation with pulmonary artery pressure values

Yigla¹,

Keidar²,

Safadi³

et al. 2004

Kidney International

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Section: Discussionmentioning

confidence: 99%

Pulmonary calcification in hemodialysis patients: Correlation with pulmonary artery pressure values

Yigla¹,

Keidar²,

Safadi³

et al. 2004

Kidney International

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“…The possibility of metastatic calcification should be considered in ATL patients associated with hypercalcemia who have abnormal shadow by roentgenogram [35, 39]. Other useful diagnostic procedures are imaging with computed tomography (CT) [35], magnetic resonance (MR) [40], and bone scintigraphy [35]. …”

Section: Metastatic Calcificationmentioning

confidence: 99%

Pathogenesis of Metastatic Calcification and Acute Pancreatitis in Adult T-Cell Leukemia under Hypercalcemic State

Senba

Kawai²,

Mori

2012

Leukemia Research and Treatment

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Human T-cell leukemia virus type-1 (HTLV-1) is the causative agent of adult T-cell leukemia (ATL). Hypercalcemia is common in patients with ATL. These patients rarely develop metastatic calcification and acute pancreatitis. The underlying pathogenesis of this condition is osteoclast hyperactivity with associated overproduction of parathyroid hormone-related protein, which results in hypercalcemia in association with bone demineralization. The discovery of the osteoclast differentiation factor receptor activator of nuclear factor-κB ligand (RANKL), its receptor RANK, and its decoy receptor osteoprotegerin (OPG), enhanced our understanding of the mechanisms of ATL-associated hypercalcemia. Macrophage inflammatory protein-1-α, tumor necrosis factor-α, interleukin-1, and interleukin-6 are important molecules that enhance the migration and differentiation of osteoclasts and the associated enhanced production of RANKL for osteoblast formation. In this paper, we focus on metastatic calcification and acute pancreatitis in ATL, highlighting recent advances in the understanding of the molecular role of the RANKL/RANK/OPG system including its interaction with various cytokines and calciotropic hormones in the regulation of osteoclastogenesis for bone resorption in hypercalcemic ATL patients.

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“…There are several reports about findings of PAM on conventional CT and HRCT. [7][8][9][10][11][12][13] To our knowledge, highresolution CT findings have not been previously reported in the Arab region.…”

Section: Felsonmentioning

confidence: 72%

Pulmonary Alveolar Microlithiasis: High-Resolution CT Scan

Abu-Ghazzeh¹

2000

Ann Saudi Med

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Case Report. MR Appearance of Pulmonary Metastatic Calcification

Abstract: We report a case of metastatic pulmonary calcification that showed hyperintense signal on T1-weighted MRI. This uncommon MR appearance of calcification is similar to the MR characteristics of calcification in the brain due to abnormal calcium metabolism.

Cited by 20 publications

References 9 publications

Pulmonary calcification in hemodialysis patients: Correlation with pulmonary artery pressure values

Pulmonary calcification in hemodialysis patients: Correlation with pulmonary artery pressure values

Pathogenesis of Metastatic Calcification and Acute Pancreatitis in Adult T-Cell Leukemia under Hypercalcemic State

Pulmonary Alveolar Microlithiasis: High-Resolution CT Scan

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