Case report of a combination of periodic disease and irritable bowel syndrome

Abstract

The article reports a case of atypical picture of a combination ofperiodic disease and irritable bowel syndrome in a 52 year old patient.

Causal Relationship between Physiological and Pathological Processes in the Brain and in the Gastrointestinal Tract: The Brain–Intestine Axis

“…Patients often have a high level of neuroticism, anxiety, depressive states, and "somatovegetative disorders." Anxiety is observed in approximately 50% of patients with functional GIT diseases [82][83][84][85][86][87][88][89][90][91]. It is known that anxiety is induced by a stress response mediated primarily through the release of corticotropin-releasing hormone from the hypothalamus.…”

“…ψυχή means soul and σ μα means body. Psychosomatic medicine is a branch of medical psychology that studies the influence of psychological factors on the occurrence, course, and outcome of somatic (body) diseases [86][87][88][89][90][91]. The Rome Process and the Rome Criteria are an international effort to collect scientific data that can help in the diagnosis and treatment of functional psychosomatic gastrointestinal disorders [82][83][84].…”

“…According to the new definition proposed by the expert council of the Rome Foundation IV Revision (2016), functional GIT diseases are disorders of the interaction of the brain and GIT. Within the framework of the new model of the formation of functional diseases of the GIT, the dysfunction of the "brain-intestine" axis at the sensory, motor, and neuroendocrine levels occupies a central place [82][83][84][85][86][87][88][89][90][91].…”