Case ‒ Temporary chemical castration in the management of recurrent priapism

Abstract

Stuttering priapism entails repeated, distinct episodes of persistent penile erection despite interval periods of detumescence. While individual episodes are acutely treated, overall management of the patient with recurrent priapism focuses on prevention of future incidents. According to American Urological Association (AUA) guidelines, systemic therapy may be used for prevention of priapism — including hormonal agents, baclofen, digoxin, and terbutaline. Other methods of management include selfinjection of sympathomimetic agents and surgical intervention with placement of a penile prosthesis.1 This case report describes long-term use of hormonal therapy in the management of stuttering priapism in a young male.

Stuttering priapism post C-spine schwannoma excision: case report

“…27 These hormonal agents include oestrogens in form of stilbesterol, gonadotropin releasing hormone agonists (GnRH), alpha reductase inhibitors, anti-androgens, and ketoconazole. [28][29][30][31][32] Antiandrogens including flutamide and bicalutamide bring suppress testosterone action by direct suppression of androgen receptors. 31 Dutasteride and finesteride, both of which are 5 alpha reductase inhibitors inhibit the conversion of testosterone to the more metabolically active dihydrotestosterone and these molecules have been utilized in the long-term prevention of stuttering priapism.…”