Cases from the Osler Medical Service at Johns Hopkins University

Losman, Julie-Aurore; Cavanaugh, Kerri L.

doi:10.1016/j.amjmed.2004.06.001

Cited by 12 publications

(3 citation statements)

References 10 publications

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“…The disease has been observed in children (1) and there is a possibility of mixed infection. As in the case reported by Losman & Cavanaugh (7), bronchoalveolar lavage has demonstrated pulmonary co-infection with S. schenckii and Pneumocystis jirovecii (7).…”

Section: Introductionsupporting

confidence: 55%

Pulmonary Sporotrichosis in Brazil: A Case Report and Review

Silva¹,

Oliveira²,

Hochhegger³

et al. 2013

Rev Patol Trop

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We report a case of primary pulmonary sporotrichosis in a 74-year-old immunocompetent woman. Culture was superior to histopathological methods in terms of diagnostic yield because the organism was not abundant in tissue sections and was visualized poorly with routine histochemical stains. Ultimately, diagnosis was made by the microbiology laboratory. Recognition of this fact is important for the proper collection and transport of clinical specimens to ensure recovery of the etiological agents of mycotic infections.

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Section: Introductionsupporting

confidence: 55%

Pulmonary Sporotrichosis in Brazil: A Case Report and Review

Silva¹,

Oliveira²,

Hochhegger³

et al. 2013

Rev Patol Trop

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“…Other unusual manifestations associated with cutaneous lesions were endocarditis, mucosal involvement (ocular and nasal), uveitis, endophthalmitis, and pulmonary and osteoarticular involvement [12,24]. Isolated involvement of the lungs and sinus has also already been described [94,95,96,97].…”

Section: Sporotrichosis In Aids Patientsmentioning

confidence: 99%

Sporotrichosis In Immunocompromised Hosts

Queiroz‐Telles

Buccheri

Benard

2019

JoF

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Sporotrichosis is a global implantation or subcutaneous mycosis caused by several members of the genus Sporothrix, a thermo-dimorphic fungus. This disease may also depict an endemic profile, especially in tropical to subtropical zones around the world. Interestingly, sporotrichosis is an anthropozoonotic disease that may be transmitted to humans by plants or by animals, especially cats. It may be associated with rather isolated or clustered cases but also with outbreaks in different periods and geographic regions. Usually, sporotrichosis affects immunocompetent hosts, presenting a chronic to subacute evolution course. Less frequently, sporotrichosis may be acquired by inhalation, leading to disseminated clinical forms. Both modes of infection may occur in immunocompromised patients, especially associated with human immunodeficiency virus (HIV) infection, but also diabetes mellitus, chronic alcoholism, steroids, anti-TNF treatment, hematologic cancer and transplanted patients. Similar to other endemic mycoses caused by dimorphic fungi, sporotrichosis in immunocompromised hosts may be associated with rather more severe clinical courses, larger fungal burden and longer periods of systemic antifungal therapy. A prolonged outbreak of cat-transmitted sporotrichosis is in progress in Brazil and potentially crossing the border to neighboring countries. This huge outbreak involves thousands of human and cats, including immunocompromised subjects affected by HIV and FIV (feline immunodeficiency virus), respectively. We reviewed the main epidemiologic, clinical, diagnostic and therapeutic aspects of sporotrichosis in immunocompromised hosts.

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“…Disseminated cutaneous sporotrichosis is primarily characterised by multiple lesions scattered over several parts of the body or the spread of haematogenous lesions. Osteoarticular (Campos-Macías et al, 2006) and pulmonary lesions (Losman & Cavanaugh, 2004;Callens et al, 2005) are the most common extracutaneous forms. All forms are rare in normal hosts.…”

Section: Introductionmentioning

confidence: 99%