Caso para diagnóstico

Abstract

A doença de Dowling-Degos é uma genodermatose rara, caracterizada principalmente por hiperpigmentação reticular progressiva de áreas flexurais. Apesar de apresentar evolução benigna, pode estar associada a neoplasias da pele. Além disso, as alterações cutâneas características potencialmente ocasionam prejuízo psicossocial, devido aos danos estéticos significativos. Os autores descrevem um caso dessa doença associado a ceratoacantoma e sintetizam os conceitos atuais sobre ela.

Coexistence of reticulate acropigmentation of Kitamura and Dowling-Degos disease

“…It is very often associated with epidermoid cysts, keratoacanthoma, squamous cells carcinoma, abscess, suppurative hidrosadenitis, seborrheic keratosis and pilonidalis cysts. 2 …”

“…3 , 4 , 5 This resembles the appearance of a solar lentigo, but with epidermal atrophy, melanin incontinence and perivascular lymphocytic infiltrate. 2 Accordingly to the similarity in clinical and histological features, many authors consider RAK and DDD different phenotypes of a single disorder. 2 In literature the authors found only few cases of overlap RAK-DDD (about a dozen), including family cases described until four generations.…”

“… 2 Accordingly to the similarity in clinical and histological features, many authors consider RAK and DDD different phenotypes of a single disorder. 2 In literature the authors found only few cases of overlap RAK-DDD (about a dozen), including family cases described until four generations. 6 , 7 …”