Cat scratch disease presenting with a retroperitoneal abscess in a patient without animal contacts

Koga, Takeharu; Taguchi, Jun; Suzuki, Minoru; Higa, Yoshiteru; Kamimura, Tomoko; Nishimura, Munetsugu; Arakawa, Masahiro

doi:10.1007/s10156-009-0725-5

Cited by 3 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinical, serological, radiological, and pathological findings are used for the diagnosis of CSD. In history, the exposure to animals, especially cats, is important medical information to suspect from CSD [ 9 ]. Serological testing for Bartonella henselae antibodies is the most cost-effective diagnostic modality with IFA to be most frequently used [ 4 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence

Atıcı

Kadayıfçı

Karaaslan

et al. 2014

Case Reports in Pediatrics

View full text Add to dashboard Cite

Typical cat-scratch disease (CSD) is characterized by local lymphadenopathy following the scratch or bite from a cat or kitten. An atypical presentation which includes liver and/or spleen lesions is rarely reported in an immunocompetent child. Systemic CSD may mimic more serious disorders like malignancy or tuberculosis. Although a diagnosis is difficult to establish in systemic CSD, an early diagnosis and an appropriate treatment are important to prevent complications. Bartonella henselae is difficult to culture, and culture is not routinely recommended. Clinical, serological, radiological, and pathological findings are used for the diagnosis of CSD. Herein we present a case of systemic CSD presenting with hepatic mass in an immunocompetent child. The differential diagnosis is made by serological and pathological evidence. He was successfully treated with gentamicin (7.5 mg/kg) and rifampin (15 mg/kg) for six weeks.

show abstract

Section: Discussionmentioning

confidence: 99%

Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence

Atıcı

Kadayıfçı

Karaaslan

et al. 2014

Case Reports in Pediatrics

View full text Add to dashboard Cite

show abstract

“…1 In addition, a variety of other unusual localized or systemic clinical manifestations can lead in some occasions to misinterpretations 2,3 and render the disease a diagnostic dispute. Although serologic analysis is the most extensively evaluated minimally invasive diagnostic technique for the diagnosis of CSD, the sensitivity of serologic tests varies from one laboratory to another ranging from nearly 100% to < 30%.…”

Section: Introductionmentioning

confidence: 99%

Seronegative cat-scratch disease diagnosed by PCR detection of Bartonella henselae DNA in lymph node samples

Chondrogiannis¹,

Vezakis²,

Derpapas³

et al. 2012

Braz J Infect Dis

View full text Add to dashboard Cite

Seronegative cat-scratch disease diagnosed by PCR detection of Bartonella henselae DNA in lymph node samples

Chondrogiannis

Vezakis

Derpapas

et al. 2012

The Brazilian Journal of Infectious Diseases

View full text Add to dashboard Cite

Cat scratch disease (CSD), the typical clinical manifestation of Bartonella infections usually follows a typical benign self-limited course. Nevertheless, a variety of unusual clinical manifestations and confusing imaging features can lead to misinterpretations and render the disease a diagnostic dispute. Routine laboratory tests exhibit varying reported sensitivity and are usually unhelpful in diagnosis, as serology fails in terms of specificity and/or sensitivity. Herein we report a case of seronegative Bartonella infection presenting as symptomatic suppurative lymphadenitis with abscess formation, which was surgically drained. Diagnosis was established by PCR analysis from lymph nodes samples obtained during the procedure. PCR detection of specific DNA fragments from lymph node biopsy provides a sensitive detection of disease. The technique should be considered for patients with suspected CSD and negative serology, since serological assays exhibit low sensitivity. In ambiguous cases, surgical exploration may provide tissue for diagnosis; it is well tolerated and affords improved recovery.

show abstract

Cat scratch disease presenting with a retroperitoneal abscess in a patient without animal contacts

Cited by 3 publications

References 14 publications

Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence

Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence

Seronegative cat-scratch disease diagnosed by PCR detection of Bartonella henselae DNA in lymph node samples

Seronegative cat-scratch disease diagnosed by PCR detection of Bartonella henselae DNA in lymph node samples

Contact Info

Product

Resources

About