Cataract and systemic disease: A review

Ang, Michael; Afshari, Natalie A.

doi:10.1111/ceo.13892

Cited by 105 publications

(89 citation statements)

References 78 publications

(178 reference statements)

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“…The proposed mechanism of cataract formation from hypocalcemia is membrane damage due to low calcium levels in the aqueous humor and increased sodium levels in the lens[ 7 ]. Sharp vigilance about the possibility of cataracts induced by hypocalcemia should be maintained, although diabetes mellitus may also contribute to cataract formation[ 8 ].…”

Section: Discussionmentioning

confidence: 99%

Reversible congestive heart failure associated with hypocalcemia: A case report

Chu¹,

Dou²,

Wang³

et al. 2021

WJCC

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BACKGROUND Hypoparathyroidism is a rare disease that may occur due to primary or secondary etiologies. The estimated incidence in the United States is 24–37/100000 person-years. Congestive heart failure associated with hypocalcemia due to hypoparathyroidism is an even rarer presentation. CASE SUMMARY Here, we present a 64-year-old woman with congestive heart failure following hypocalcemia. The patient was transferred to our emergency department with complaints of rapidly progressive dyspnea, shortness of breath and heaviness of the chest for 4 d. She had a history of undergoing thyroidectomy and partial tracheotomy 2 years prior due to a malignant thyroid tumor. Muscle spasms had been present 1 year ago, and cataracts were treated with intraocular lens replacement in both eyes. Most tests were within normal ranges, except serum calcium at 1.33 mmol/L (2.20–2.65 mmol/L), ionized calcium at 0.69 mmol/L (1.15–1.29 mmol/L), and parathyroid hormone at < 1.0 pg/mL (12–88 pg/mL). Echocardiography revealed an ejection fraction of 28.48%. Cardiac function was quickly reversed by restoring the serum calcium concentration. Significant improvements were noted with an ejection fraction of up to 48.50% at follow-up. CONCLUSION For patients with potential hypocalcemia, monitoring calcium levels and dealing with hypocalcemia in time to avoid serious complications are important.

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Section: Discussionmentioning

confidence: 99%

Reversible congestive heart failure associated with hypocalcemia: A case report

Chu¹,

Dou²,

Wang³

et al. 2021

WJCC

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“…An outline of cataracts and systematic disease is described by Ang and Afshari [11]. They studied the different epidemiologic for age-related cataracts including age and sex.…”

Section: Related Workmentioning

confidence: 99%

Recognition of Ocular Disease Based Optimized VGG-Net Models

Salem

Negm

Shams

et al. 2021

Studies in Computational Intelligence

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The detection of ocular diseases is the most interesting point for the Optometrist. Due to the cost of the devices that discover and classify the different types of ocular disease. Artificial Intelligence (AI) based image processing and Machine Learning are currently utilized to classify and detect ocular disease. In this chapter, we present an improved classification model based on an improved VGG-Net to classify the ocular disease of the stored eye image datasets. The dataset was collected and prepared to generate the image list and then the data are divided into 80% training and the remaining 20% for testing. We highlighted to classify the cataract and diabetes disease from the eye ocular images. The proposed pretrained model is tested based on deep neural networks based on VGGNet. We utilized VGGNet-16 and VGGNet-19 and applied the Adam optimizer to improve the results of VGGNet and tackle the overfitting problem. The evaluation results of the proposed VGGNet-19 based Adam optimizer indicated that the superiority rather than the optimized VGGNet-16 for cataracts and VGGNet-19 is superior to VGGNet-19 for diabetes.

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“…According to previous literature, age is by far the major risk factor for cataract 4 . Female sex is another non‐modifiable risk factor related to age‐related cataract, with a relative risk ranging 1.1–1.6 5 . In addition, the development of cataract was associated with systemic diseases, including diabetic mellitus, hypertension, metabolic syndrome, and renal impairment 5 .…”

Section: Introductionmentioning

confidence: 99%

“…4 Female sex is another nonmodifiable risk factor related to age-related cataract, with a relative risk ranging 1.1-1.6. 5 In addition, the development of cataract was associated with systemic diseases, including diabetic mellitus, hypertension, metabolic syndrome, and renal impairment. 5 In a review of the literature, few articles described the association between psoriasis and cataract.…”

mentioning

confidence: 99%

Risk of incident cataract in patients with psoriasis: A population‐based cohort study

Cheng

2021

The Journal of Dermatology

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Patients with psoriasis are predisposed to ocular complications. However, there is a paucity of data addressing the association between psoriasis and subsequent cataract development. The present study was conducted to evaluate whether there is an increased risk of cataract among patients with psoriasis. The study subjects of this cohort study were selected based on Chang Gung Research Database from 1 January 2003 to 31 December 2012. Follow‐up ended 31 December 2017. Patients aged 20 years and older with psoriasis were enrolled. The participants of the control group were selected by matching with sex, age, and index date at a 4:1 ratio. Patients previously diagnosed with cataract were excluded. The hazard ratios associated with psoriasis were estimated using Cox regression analysis with competitive risk model. We also evaluated the relationship between the risk of cataract and systemic therapies as well as phototherapy and topical corticosteroid in patients with psoriasis. A total of 6823 patients with psoriasis and 27 292 matched controls were enrolled in the study. The psoriasis group had higher incidence rates than the control group for cataract (44.08 vs 19.45 per 10 000 person‐years; adjusted hazard ratio, 1.778 [95% confidence interval, 1.530–2.066; p < 0.001]). Psoriatic patients receiving phototherapy for more than 200 sessions had a higher risk of cataract (adjusted hazard ratio, 2.933; 95% confidence interval, 1.192–7.218; p = 0.019), especially those receiving narrowband ultraviolet B therapy. The present study demonstrated a positive association between psoriasis and cataract. Physicians should be alert to visual function in patients with psoriasis, especially those receiving long‐term phototherapy.

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Cataract and systemic disease: A review

Cited by 105 publications

References 78 publications

Reversible congestive heart failure associated with hypocalcemia: A case report

Reversible congestive heart failure associated with hypocalcemia: A case report

Recognition of Ocular Disease Based Optimized VGG-Net Models

Risk of incident cataract in patients with psoriasis: A population‐based cohort study

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