Cataract Surgery in Children With Uveitis: Retrospective Analysis of Intraocular Lens Implantation With Anterior Optic Capture

Abstract

The technique of cataract extraction with IOL placement and anterior prolapse of the optic through the anterior capsulorhexis shows promise to be a safe and viable option for pediatric patients with chronic uveitis treated with systemic immunotherapy.

Cataract Surgery with or without Intraocular Lens Implantation in Pediatric Uveitis: A Systematic Review with Meta-Analyses

“…Taken together, studies found that cataract surgery, regardless of IOL implantation, generally improved vision. Nearly all studies specifically highlighted the need for intensive immunosuppressive treatment and control of uveitis after cataract surgery, but it was unclear whether it was a question of sustaining preexisting regimen or based on a change in the need for controlling the uveitis [16,20,21,[32][33][34][35][36].…”

“…Nine studies provided eligible and comparable data for the meta-analyses [16,20,21,30,[32][33][34][35][36]. ese studies collectively summarized data on 256 eyes: 153 eyes underwent IOL implantation and 103 eyes were aphakic.…”

“…Eight studies provided relevant data for the primary outcome [16,20,21,[32][33][34][35][36]. O'Rourke et al [34] provided only data on a single eye with aphakia, which leads to SD � 0, and therefore this study was ineligible for the meta-analysis for analytical reasons [34].…”

“…ree studies reported that the uveitis was quiescent 3 months prior to surgery in all eyes [21,35,36], one study reported that the uveitis was inactive in 6 months prior to surgery [34], and one study reported absence of inflammation in 3 months prior to surgery except one eye with absence of inflammation for 2 months [33].…”

“…Uveitis subtypes Artigas et al [30] JIA-associated uveitis (11 eyes) Beal and Wang [31] Any uveitis (32 eyes) BenEzra and Cohen [31] JIA-associated (9 eyes) and non-JIA-associated uveitis (11 eyes) Guindolet et al [32] JIA-associated (9 eyes) and non-JIA-associated uveitis (11 eyes) Kemp et al [33] JIA-associated (7 eyes) uveitis, juvenile xanthogranulomatosis (1 eye), and idiopathic uveitis (1 eye) Kotaniemi and Penttilä [20] JIA-associated uveitis ( symmetrical and the sensitivity analysis demonstrated robustness of the findings (Supplementary file 6).…”