Catechol-chitosan/polyacrylamide hydrogel wound dressing for regulating local inflammation

Recent advances in responsive hydrogels for diabetic wound healing

“…Recently, smart hydrogels with stimulus-responsive functions have attracted considerable attention. Briefly, stimulus-responsive hydrogels can respond to internal physiological signals (i.e., temperature [ 28 , 29 ], pH [ 30 , 31 ], redox [ 32 , 33 ], glucose [ 34 , 35 ], or enzymes [ 36 , 37 ]), external stimuli (i.e., temperature [ 38 , 39 ], magnetic field [ 40 , 41 ], pressure [ 42 , 43 ], reactive oxygen species (ROS) [ 44 , 45 ], light [ 46 , 47 ] and electric field [ 48 , 49 ]) or a combination of the above, which can reversibly or irreversibly change the physical properties or chemical structure ( Fig. 2 ).…”

Mussel-inspired adhesive hydrogels for local immunomodulation

“…Some researchers have loaded immunomodulatory drugs into hydrogels to promote skin healing. 118,119 Lu et al prepared a dual-responsive hydrogel drug delivery system based on polyacrylamide, catechol-chitosan, and acetalized cyclodextrin nanoparticles to release Resolvin E1, a specialized pro-resolving lipid mediator that can influence the transformation of the macrophage phenotype via changing the leukotriene ratio. 118 Sun et al developed a new zinc alginate hydrogel embedded with hollow dopamine nanoparticles loaded with the potent pro-healing peptide RL-QN15.…”

Recent Reports on Polysaccharide-Based Materials for Drug Delivery

“…Many carriers composed of chitosan and other polymers are dedicated to wound healing [ 103 , 104 , 105 ]. Polyvinyl-CS hydrogels with lignin nanoparticles were synthesized to analyze the influence of lignin on the physicochemical, antibacterial, and antioxidant properties of the composite material [ 106 ].…”