2024
DOI: 10.21203/rs.3.rs-3929469/v1
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Causal relationship between telomere length and renal cell carcinoma and prognostic modeling of ccRCC based on telomere- related lncRNAs

Hao Chen,
Jianfeng Zeng,
Li Li

Abstract: Background Telomeres have been demonstrated to be critical in the development of multiple tumors. However, the association of telomere-related lncRNAs with clear cell renal cell carcinoma (ccRCC) and their prognostic roles in ccRCC patients remain unknown. Methods Exposure data was obtained from GWAS database. Two-sample mendelian randomization (MR) was used to test for causal associations between telomere length and renal cell carcinoma. Expression matrix and clinicopathological data of ccRCC patients were… Show more

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