Causas y componentes del síndrome metabólico en receptores de trasplante renal desde una perspectiva de género

Salvador, Adelina Martín; Castillo, Rafael Fernández; García, Inmaculada García; Cordero, María José Aguilar; Soto, Juan Antonio Bravo

doi:10.20960/nh.1717

Nutr Hosp

2018

DOI: 10.20960/nh.1717

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Causas y componentes del síndrome metabólico en receptores de trasplante renal desde una perspectiva de género

Adelina Martín Salvador¹,

Rafael Fernández Castillo²,

Inmaculada García García³

et al.

Abstract: Introducción: la aparición del síndrome metabólico (SM) entre los receptores renales es una de las mayores complicaciones postrasplante y se asocia con un mayor riesgo de fracaso del injerto y altas tasas de obesidad y diabetes de nueva aparición.Objetivo: el objetivo de este trabajo es identificar la relación entre la tasa de filtración glomerular medida por dos métodos distintos y los componentes del síndrome metabólico y sus combinaciones en pacientes trasplantados renales según género.Material y método: la… Show more

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Cited by 3 publications

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Metabolic Syndrome and Dietary Intake are Associated With Quality of Life in Kidney Transplant Recipients

Nguyen,

Mat Daud,

Abd. Talib

et al. 2023

Transplantation Proceedings

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Metabolic Syndrome and Dietary Intake are Associated With Quality of Life in Kidney Transplant Recipients

Nguyen,

Mat Daud,

Abd. Talib

et al. 2023

Transplantation Proceedings

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Cardiometabolic risk factor clusters in older adults using latent class analysis on the Bushehr elderly health program

Afrashteh,

Jalalian,

Daneshi

et al. 2024

Sci Rep

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Metabolic syndrome (MetS), comprising obesity, insulin resistance, hypertension, and dyslipidemia, increases the risk of type II diabetes mellitus and cardiovascular disease. This study aimed to identify the prevalence and determinants of specific clusters of the MetS components and tobacco consumption among older adults in Iran. The current study was conducted in the second stage of the Bushehr Elderly Health (BEH) program in southern Iran—a population-based cohort including 2424 subjects aged ≥ 60 years. Latent class analysis (LCA) was used to identify MetS and tobacco consumption patterns. Multinomial logistic regression was conducted to investigate factors associated with each MetS class, including sociodemographic and behavioral variables. Out of 2424 individuals, the overall percentage of people with one or more components of MetS or current tobacco use was 57.8% and 20.8%, respectively. The mean (SD) age of all participants was 69.3(6.4) years. LCA ascertained the presence of four latent classes: class 1 (“low risk”; with a prevalence of 35.3%), class 2 (“MetS with medication-controlled diabetes”; 11.1%), class 3 (“high risk of MetS and associated medication use”; 27.1%), and class 4 (“central obesity and treated hypertension”; 26.4%). Compared to participants with a body mass index (BMI) < 30, participants with BMI ≥ 30 were more likely to belong to class 3 (OR 1.91, 95% CI 1.31–2.79) and class 4 (OR 1.49, 95% CI 1.06–2.08). Polypharmacy was associated with membership in class 2 (OR 2.07, 95% CI 1.12–3.81), class 3 (OR 9.77, 95% CI 6.12–15.59), and class 4 (OR 1.76, 95% CI 1.07–2.91). The elevated triglyceride-glucose index was associated with membership in class 2 (OR 12.33, 95% CI 7.75–19.61) and class 3 (OR 12.04, 95% CI 8.31–17.45). Individuals with poor self-related health were more likely to belong to class 3 (OR 1.43; 95% CI 1.08–1.93). Four classes were identified among older adults in Iran with distinct patterns of cardiometabolic risk factors. Segmenting elderly individuals into these cardiometabolic categories has the potential to enhance the monitoring and management of cardiometabolic risk factors. This strategy may help reduce the severe outcomes of metabolic syndrome in this susceptible population.

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Study of weight and body mass index on graft loss after transplant over 5 years of evolution

et al. 2020

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Patients frequently experience a weight gain after organ transplantation. This increase in weight is the result of multiple factors, and is usually intensified by glucocorticoids and immunosuppressive drugs. It can also delay graft function and cause serious health problems. The objective of this study was to study the obesity as well as its causes and consequences in kidney transplant patients. The sample population consisted of 282 renal transplant patients, 170 men and 112 women, 18-74 years of age, who were monitored over a period of five years. For the purposes of our research, the patients were divided into two groups: (1) normal weight 18.5 ≤ BMI <25; (2) overweight 25 ≤ BMI ≤30. The association between BMI as an independent variable and graft survival was determined by means of a Cox regression analysis. Overweight patients were characterized by a higher comorbidity prevalence. In the Cox multivariate analysis, the initial BMI, evaluated as a continuous variable continued to be an independent predictor of delayed graft function and chronic nephropathy. This study evaluated the BMI as a continuous value instead of a categorical value. In conclusion, our results suggest that an increase in BMI without categorical variation can be an independent risk factor for graft loss. Consequently, obesity prevention for renal transplant patients should include dietary counseling and management, moderate physical activity, and steroid minimization.

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Causas y componentes del síndrome metabólico en receptores de trasplante renal desde una perspectiva de género

Cited by 3 publications

References 0 publications

Metabolic Syndrome and Dietary Intake are Associated With Quality of Life in Kidney Transplant Recipients

Metabolic Syndrome and Dietary Intake are Associated With Quality of Life in Kidney Transplant Recipients

Cardiometabolic risk factor clusters in older adults using latent class analysis on the Bushehr elderly health program

Study of weight and body mass index on graft loss after transplant over 5 years of evolution

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