Cause-Specific Mortality Trends Following Total Hip and Knee Arthroplasty

Michet, Clement J.; Schleck, Cathy D.; Larson, Dirk R.; Kremers, Hilal Maradit; Berry, Daniel J.; Lewallen, David G.

doi:10.1016/j.arth.2016.10.009

Cited by 22 publications

(14 citation statements)

References 19 publications

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“…Of all 1504 patients, only a few participants were reported to withdraw for side effects, and most fluoroscopicor ultrasound-guided hip IAST procedures were very well tolerated by participants. However, whether the injection would influence the prevalence after the future THR is still under caution [27,28] and needs to be further studied.…”

Section: Discussionmentioning

confidence: 99%

Intra‐Articular Steroid Injection for Patients with Hip Osteoarthritis: A Systematic Review and Meta‐Analysis

Zhong

Zhao

Lin

et al. 2020

BioMed Research International

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Purpose. The aim of this current review was to confirm the efficacy of intra-articular steroid therapy (IAST) for patients with hip osteoarthritis (OA) and discuss the duration and influential factors of IAST. Methods. Online databases (Medline, EMBASE, and Web of Science) were searched from inception to May 2019. Both randomized controlled trials (RCTs) and noncontrolled trials assessing the efficacy of hip IAST on pain were included. Common demographics data were extracted using a standardized form. Quality was assessed on the basis of Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence. Results. 12 trials met the inclusion criteria. According to data from individual trials, IAST had significant efficacy on hip OA in both immediate and delay pain reduction, which persisted up to 12 weeks after IAST. The influences of the baseline severity of hip OA or synovitis and injection dose or volume on the clinical outcome of IAST were still controversial. The IAST appeared to be well tolerant by most of the participants. Conclusion. IAST was proved to be an efficacious therapy in both immediate and delay pain reduction for hip OA patients within 12 weeks. The longer follow-up data of efficacy and safety and potentially influential factors are still unclear and needed further confirmation.

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Section: Discussionmentioning

confidence: 99%

Intra‐Articular Steroid Injection for Patients with Hip Osteoarthritis: A Systematic Review and Meta‐Analysis

Zhong

Zhao

Lin

et al. 2020

BioMed Research International

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“…Mortality in these patients is lower than in the general population (Michet et al. 2017 ). Our hypothesis was therefore that risk factors for mortality in these patients might appear after—and not before—surgery.…”

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confidence: 92%

Comorbidity does not predict long-term mortality after total hip arthroplasty

et al. 2017

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Background and purposeIn-hospital death following total hip arthroplasty (THA) is related to comorbidity. The long-term effect of comorbidity on all-cause mortality is, however, unknown for this group of patients and it was investigated in this study.Patients and methodsWe used data from the Swedish Hip Arthroplasty Register, linked to the National Patient Register from the National Board of Health and Welfare, for patients operated on with THA in 1999–2012. We identified 120,836 THAs that could be included in the study. We evaluated the predictive power of the Charlson and Elixhauser comorbidity indices on mortality, using concordance indices calculated after 5, 8, and 14 years after THA.ResultsAll comorbidity indices performed poorly as predictors, in fact worse than a base model with age and sex only. Elixhauser was, however, the least bad choice and it predicted mortality with concordance indices 0.59, 0.58, and 0.56 for 5, 8, and 14 years after THA.InterpretationComorbidity indices are poor predictors of long-term mortality after THA.

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“…There are reports comparing mortality by each cause. 13,14 Cardiovascular disease (CVD) is a well-known problem associated with osteoarthritis due to impaired mobility. Because TKA relieves pain and improves walking ability, CVD-related events are reduced in TKA patients.…”

Section: Introductionmentioning

confidence: 99%

Total knee arthroplasty reduces the risk of mortality in osteoarthritis patients up to 12 years: A Korean national cohort longitudinal follow-up study

Choi

Kwon

Kim

et al. 2020

J Orthop Surg (Hong Kong)

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Introduction: Mortality rates and causes of death after total knee arthroplasty (TKA) are of great interest to surgeons. However, there is a shortage of studies regarding those of the Asian population. The aim of this study was to compare the mortality rate and causes of death in patients after TKA to the general population. Methods: National sample cohort data from the Korean Health Insurance Review and Assessment Service were used. In this study, 1:4 matched patients after TKA (TKA group: 5072) and general participants (control group: 20,288) were selected as subjects. Their average follow-up duration was 57.2 months ranging from a year up to 12 years. The matches were processed for age, gender, income, region of residence, and past medical history. Mortality rates and causes of death were compared between groups. Regarding the mortality rates, we also performed subgroup analyses according to age. Results: Adjusted hazard ratio (HR) of the TKA group for mortality rate was less than 1 with significance (adjusted HR = 0.61 (95% confidence interval = 0.54–0.70, p < 0.001)). The ratios were less than 1 for both age groups (<70 and ≥70 years), respectively; however, for patients under 70, they were insignificant. Among the 11 major causes of death, the circulatory disease showed the most significantly reduced mortality rate for the TKA group compared to the control group. The neoplasm was the only other cause with a significantly reduced mortality rate for the TKA group. Conclusion: The mortality rate in the TKA group was significantly lower than in the control group up to 12 years after the surgery in Korea. Among the major causes of death, circulatory disease and neoplasm showed a significant reduction in the mortality rate of the TKA group compared with the control group.

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Cause-Specific Mortality Trends Following Total Hip and Knee Arthroplasty

Cited by 22 publications

References 19 publications

Intra‐Articular Steroid Injection for Patients with Hip Osteoarthritis: A Systematic Review and Meta‐Analysis

Intra‐Articular Steroid Injection for Patients with Hip Osteoarthritis: A Systematic Review and Meta‐Analysis

Comorbidity does not predict long-term mortality after total hip arthroplasty

Total knee arthroplasty reduces the risk of mortality in osteoarthritis patients up to 12 years: A Korean national cohort longitudinal follow-up study

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