Causes, comorbidities and current status of chronic kidney disease: A community perspective from North Kerala

Jacob, Sujamol; Raveendran, Rini; Kannan, Suthanthira

doi:10.4103/jfmpc.jfmpc_478_19

Cited by 10 publications

(7 citation statements)

References 18 publications

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“…In our analysis, CKD a common comorbidity of diabetes [ 23 ] and hypertension [ 24 ], increased almost two times the risk of death in comparison to people without this disease. Cheng et al [ 25 ] reported that 13.1% of the people admitted to hospitalization in China had kidney failure.…”

Section: Discussionmentioning

confidence: 94%

A survival analysis of COVID-19 in the Mexican population

et al. 2020

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Background At present, the Americas report the largest number of cases of COVID-19 worldwide. In this region, Mexico is the third country with most deaths (20,781 total deaths). A sum that may be explained by the high proportion of people over 50 and the high rate of chronic diseases. The aim of this analysis is to investigate the risk factors associated with COVID-19 deaths in Mexican population using survival analysis. Methods Our analysis includes all confirmed COVID-19 cases contained in the dataset published by the Epidemiological Surveillance System for Viral Respiratory Diseases of the Mexican Ministry of Health. We applied survival analysis to investigate the impact of COVID-19 on the Mexican population. From this analysis, we plotted Kaplan-Meier curves, and constructed a Cox proportional hazard model. Results The analysis included the register of 16,752 confirmed cases of COVID-19 with mean age 46.55 ± 15.55 years; 58.02% (n = 9719) men, and 9.37% (n = 1569) deaths. Male sex, older age, chronic kidney disease, pneumonia, hospitalization, intensive care unit admission, intubation, and health care in public health services, were independent factors increasing the risk of death due to COVID-19 (p < 0.001). Conclusions The risk of dying at any time during follow-up was clearly higher for men, individuals in older age groups, people with chronic kidney disease, and people hospitalized in public health services.

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Section: Discussionmentioning

confidence: 94%

A survival analysis of COVID-19 in the Mexican population

et al. 2020

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“…In our analysis CKD, a common comorbidity of diabetes (19) and hypertension (20), increased 1.85 times the risk of death in comparison to people without this disease. Cheng et al (21) reported that 13.1% of the people admitted to hospitalization in China had kidney failure.…”

Section: Discussionmentioning

confidence: 82%

A survival analysis of COVID-19 in the Mexican population

Salinas-Escudero

Carrillo-Vega

Granados-García

et al. 2020

Preprint

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Background. At present, the Americas region contributes to the largest number of cases of COVID-19 worldwide. In this area, Mexico is in third place respecting deaths (20,781 total deaths), rate that may be explained by the high proportion of the population over 50 years and the rate of chronic diseases. The aim of the present work was estimate the risk factors associated with the death rate, considering the time between symptoms onset and the death occurrence, in the Mexican population. Methods. Information of all the confirmed cases for COVID-19 reported on the public dataset released by the Epidemiological Surveillance System for Viral Respiratory Diseases of the Mexican Ministry of Health was analyzed. Kapplan-Meier curves were plotted, and a Cox proportional hazard model was constructed. Results. The analysis included 16,752 registries of confirmed cases of COVID-19 with mean age 46.55±15.55 years; 58.02% (n=9719) men and 9.37% (n=1,569) died. Men (H.R. 1.21, p<0.01, 95% C.I. 1.09-1.35), older age (H.R. 8.24, p<0.01, 95% C.I. 4.22-16.10), CKD (H.R. 1.85, p<0.01, 95% C.I. 1.51-2.25), pneumonia (H.R. 2.07, p<0.01, 95% C.I. 1.81-2.38), hospitalization and ICU admissions (H.R. 5.86, p<0.01, 95% C.I. 4.81-7.14, and H.R. 1.32, p<0.01, 95% C.I. 1.12-1.55, respectively), intubation (H.R. 2.93, p<0.01, 95% C.I. 2.50-3.45) and health care in public health services (more than twice the risk, p<0.01), were independent factors increasing the risk of death due to COVID-19. Conclusions. The risk of dying at any time during follow-up was especially higher in men, individuals at the older age groups, with chronic kidney disease and people hospitalized in the public health services.

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“…Diabetes is one of the most common comorbidities in ESRD and should be considered when devising transplant treatment plans. 12,13 Diabetes was associated with postoperative urinary retention, UTI, and urosepsis. However, it did not factor into the linear regression models as significant.…”

Section: Discussionmentioning

confidence: 97%

A Contemporary Evaluation of Urological Outcomes After Renal Transplantation

et al. 2023

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Introduction:Urological surgery after renal transplantation leaves patients at risk of infection and further urological complications. Our objective was to discern patient factors associated with adverse outcomes following renal transplantation to identify patients who would benefit from close urological follow-up.Methods:Retrospective chart review was conducted for patients undergoing renal transplantation between August 1, 2016 and July 30, 2019 at a tertiary care academic center. Data on patient demographics, medical history, and surgical history were collected. Primary outcomes observed were urinary tract infection, urosepsis, urinary retention, unexpected urology visit, and urological procedures within 3 months of transplant. Variables determined significant by hypothesis testing were used in logistic regression modeling for each primary outcome.Results:Of the 789 renal transplant patients, 217 (27.5%) developed postoperative urinary tract infection and 124 (15.7%) developed postoperative urosepsis. Patients with postoperative urinary tract infection were more likely to be female (OR 2.2, P < .01), have pre-existing prostate cancer (OR 3.1, P < .01), and recurrent urinary tract infections (OR 2.1, P < .01). After renal transplant, unexpected urology visits were observed in 191 (24.2%) patients, and urological procedures were performed in 65 (8.2%) patients. Postoperative urinary retention was noted in 47 (6.0%) patients and seen more often in patients with benign prostatic hyperplasia (OR 2.8, P = .033) and prior prostate surgery (OR 3.0, P = .072).Conclusions:Identifiable risk factors associated with urological complications after renal transplantation include benign prostatic hyperplasia, prostate cancer, urinary retention, and recurrent urinary tract infections. Female renal transplant patients are at increased risk of postoperative urinary tract infection and urosepsis. These patient subsets would benefit from establishing urological care and pre-transplant urological evaluation including urinalysis, urine cultures, urodynamic studies, and close follow-up post-transplant.

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Causes, comorbidities and current status of chronic kidney disease: A community perspective from North Kerala

Cited by 10 publications

References 18 publications

A survival analysis of COVID-19 in the Mexican population

A survival analysis of COVID-19 in the Mexican population

A survival analysis of COVID-19 in the Mexican population

A Contemporary Evaluation of Urological Outcomes After Renal Transplantation

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