Cavernous Sinus Syndrome Caused by Metastatic Colon Carcinoma

Öneç, Birgül; Öksüzoğlu, Berna; Hatipoğlu, Hatice Gül; Öneç, Kürşad; Azak, Alper; Zengi̇n, Nurullah

doi:10.3816/ccc.2007.n.028

Cited by 15 publications

(11 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the two reported cases of CSS due to distant metastases of known CRC, both patients died shortly after diagnosis despite treatment with radiochemotherapy [6,7].…”

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Sixth nerve palsy as the presenting symptom of metastatic colon carcinoma

2010

View full text Add to dashboard Cite

Isolated cranial mononeuropathies in patients over 50 years of age most commonly result from microvascular ischemic demyelination. A 51-year-old female without vasculopathic risk factors presented with isolated sixth nerve palsy. Magnetic resonance imaging (MRI) of the brain and orbits revealed a cavernous sinus lesion that was diagnosed as a meningioma. Laboratory tests showed abnormal liver function, and an abdominal computerized tomogram demonstrated an obstructive colonic mass with liver metastasis. The pathology tests of specimens taken during a laparotomy diagnosed colon adenocarcinoma. The MRI interpretation was changed to cavernous sinus metastasis from a primary adenocarcinoma of the colon. This case had common cranial nerve symptoms but with a very rare etiology, emphasizing the importance of a high index of suspicion of remote origins in patients with isolated sixth nerve palsy and no atherosclerotic risk factors.

show abstract

“…In the two reported cases of CSS due to distant metastases of known CRC, both patients died shortly after diagnosis despite treatment with radiochemotherapy [6,7].…”

Section: Discussionmentioning

confidence: 97%

“…Metastases from distant sites also include breast, lung, lymphoma, prostate, melanoma and (rarely) colon, with only a few case reports appearing in the literature [6,7]. Metastasis was not the presenting symptom in any of them.…”

Section: Discussionmentioning

confidence: 99%

Sixth nerve palsy as the presenting symptom of metastatic colon carcinoma

2010

View full text Add to dashboard Cite

show abstract

“…Among them, the oculomotor and abducens nerves are most frequently involved, followed by the trochlear nerve 7,8 . Diplopia, ptosis, ophthalmoplegia, decreased corneal reflex, dysesthesias, hypesthesia, headache, retroorbital pain and facial pain are commonly presenting symptoms 3 .…”

Section: Discussionmentioning

confidence: 99%

“…Generally, radiation therapy is performed as standard treatment and often leads to improvement of symptoms and alleviation of pain 13 . However, the prognosis is very poor and the median survival is reported to be 4∼4.5 months from the onset of symptoms 3,5 . Therefore, lack of radiologic abnormalities should not be taken as evidence for the absence of metastatic lesions and treatment should be started under a clinical diagnosis because local treatment such as radiotherapy may relieve or alleviate the symptoms completely 11,16 .…”

Section: Discussionmentioning

confidence: 99%

“…The etiology of cavernous sinus syndrome is difficult to find and diverse including bacterial or fungal infections, non-infectious inflammation, vascular lesions, and neoplasms 1 . It is relatively rare that metastasis to the parasellar region or cavernous sinus from distant site occur in patients with systemic cancer 2,3 . In patients with cavernous sinus metastasis, the most common primary sites (sites other than the head and neck) are the breast, prostate, and lung 4,5 .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cavernous Sinus Metastasis of Non-Small Cell Lung Cancer

Ahn¹,

Yang²,

Kim³

et al. 2010

Tuberc Respir Dis

View full text Add to dashboard Cite

Progressive ptosis and headache developed in a 50-year-old woman with non-small cell lung cancer. Although brain magnetic resonance imaging showed improved cerebellar metastasis after prior radiotherapy without any other abnormality, the follow-up examination taken 6 months later revealed metastasis to the cavernous sinus. The diagnosis of metastasis to the cavernous sinus is often difficult because it is a very rare manifestation of lung cancer, and symptoms can occur prior to developing a radiologically detectable lesion. Therefore, when a strong clinical suspicion of cavernous sinus metastasis exists, thorough neurologic examination and serial brain imaging should be followed up to avoid overlooking the lesion.

show abstract

Venous drainage of the spine and spinal cord: A comprehensive review of its history, embryology, anatomy, physiology, and pathology

et al. 2014

View full text Add to dashboard Cite

Venous drainage of the spine and spinal cord is accomplished through a complex network of venous structures compartmentalized to intrinsic, extrinsic, and extradural systems. As the literature on this topic is scarce, the following review was performed to summarize the available literature into a single coherent format. The medical literature on the spinal venous system was reviewed using online sources as well as historical documents that were not available online in regard to history, embryology, anatomy, and physiology with a particular emphasis on the pathology affecting this system. The spinal venous system is complex and variable. Proper understanding of all aspects is critical for the management of the pathology that results from its failure.

show abstract

Cavernous Sinus Syndrome Caused by Metastatic Colon Carcinoma

Cited by 15 publications

References 11 publications

Sixth nerve palsy as the presenting symptom of metastatic colon carcinoma

Sixth nerve palsy as the presenting symptom of metastatic colon carcinoma

Cavernous Sinus Metastasis of Non-Small Cell Lung Cancer

Venous drainage of the spine and spinal cord: A comprehensive review of its history, embryology, anatomy, physiology, and pathology

Contact Info

Product

Resources

About