Cavernous Sinus Thrombosis and Blindness Complicating Dental Infection

Ng, Emily Ming Choo; Othman, Othmaliza; Li, Chan; Bahari, Nor Akmal

doi:10.7759/cureus.21318

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…Ischemic optic neuropathy may complicate CST and results in permanent visual loss. [ 14 ] However, we lacked sufficient angiographic images to support this argument. Besides, we presumed that if the hypercoagulable state was related to the recent vaccination, prolonged INR due to warfarin consumption and hyperthyroidism conditions could also lead to thrombotic events.…”

Section: Discussionmentioning

confidence: 99%

A case of aseptic bilateral cavernous sinus thrombosis following a recent inactivated SARS-CoV-2 vaccination

Nora¹,

Nusanti²,

Putera³

et al. 2022

Taiwan Journal of Ophthalmology

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This case report aims to describe the first report of bilateral aseptic cavernous sinus thrombosis (CST) with a recent history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. A 50-year-old woman presented with bilateral proptosis, decreased vision, and ophthalmoplegia 16 days following CoronaVac ® vaccine. The visual acuity of the left eye was 20/150, while the right eye was no light perception with a hyperemic optic nerve head. She had a history of hyperthyroidism and currently on warfarin consumption. Laboratory results depicted elevated free T4, free T3, international normalized ratio, and low protein S and C. Magnetic resonance imaging showed bilateral CST, and high-dose methylprednisolone along with fondaparinux was given. The symptoms were significantly resolved, with the visual acuity of the left eye being improved to 20/20 but not the right eye. Bilateral CST has not been previously reported following inactivated SARS-CoV-2 vaccination. The underlying systemic conditions should be taken into consideration for the possibility of the inactivated SARS-CoV-2 vaccine-related event.

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Section: Discussionmentioning

confidence: 99%

A case of aseptic bilateral cavernous sinus thrombosis following a recent inactivated SARS-CoV-2 vaccination

Nora¹,

Nusanti²,

Putera³

et al. 2022

Taiwan Journal of Ophthalmology

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“…Therefore, clinicians should suspect SCST in patients with multiple ophthalmoplegia, proptosis, ptosis, fever, and sensory impairment in the ophthalmic and maxillary regions. 36 Indispensable for a definitive diagnosis is brain CT, or magnetic resonance imaging. 36 …”

Section: Clinical and Research Consequences: Complications Associated...mentioning

confidence: 99%

Serious Complications and Treatment Strategies Associated with Odontogenic Infections

Acar Evsen,

Candan

2024

The Eurasian Journal of Medicine

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Dental caries is a prevalent chronic disease on a global scale, affecting individuals at some point in their lives. Odontogenic infections (OIs) arise from dental origins and can be caused by several pathologies, such as caries, trauma, pericoronitis, gingivitis, and iatrogenic factors. Dental caries is a prevalent chronic disease on a global scale, affecting individuals at some point in their lives. The objective of this review is to provide clinicians with information regarding uncommon yet severe complications that can arise from OIs. These complications include necrotizing fasciitis, cerebral abscess, orbital cellulitis, descending necrotizing mediastinitis, sepsis, and cavernous sinus thrombosis. The review encompasses the origin of complications, the progression of infection, as well as their diagnosis and treatment. Early diagnosis and treatment are crucial for determining the clinical course of odontogenic infections. Treatment and diagnosis of OIs in a timely manner prevent complications. Dental professionals play a critical role in the prevention and assessment of OIs, particularly those that are progressive and difficult to treat and identify.

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“…2 Therefore, early detection of the disease and adequate therapy are very important to reduce the possibility of complications. 5…”

Section: Introductionmentioning

confidence: 99%

Septic Cavernous Sinus Thrombosis (CST) with Blindness Caused by Odontogenic Infection – A Case Report

Valentine

Adrianto²,

Setyowatie³

2023

magna-neurologica

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Introduction: Septic cavernous sinus thrombosis (CST) is a rare thrombosis, but severe, causing damage to all nerves inside the cavernous sinus. The incidence rate of CST is estimated at two to four per million people per year. The symptom usually varies, gradually worsening, making diagnosis harder and potentially making permanent disability. Early detection and prompt treatment are very important to lower the morbidity rate. Case: Tn. M had complained of multiple headaches attacks since 8 months ago before being admitted followed by diplopia. Complaints had worsened 3 months before with the loss of vision in the left eye. MRI showed left thrombosis sinus cavernous. The terrible headache was scaled 8-9 with VAS score. The patient’s left eye was found proptosis palpebra, with anisocoria and mydriasis followed by no direct light reflex also indirect light reflex, visual acuity of the left eye is no light response, whereas the patient’s right eye is normal. On the patient’s left eye was found gaze palsy sinistra. The abnormal blood result was leucocytosis and thrombocytosis. The patient was given fondaparinux once a day with a dose of 6000 units subcutaneously for 5 days. After that, the headache was decreased significantly. The patient underwent 5 tooth extraction done by mouth surgeon after being discharged. The patient was given 20 mg rivaroxaban per day for three weeks, then 10mg per day for three months, and evaluated with MRV again. Conclusion: CST is still very rare but very lethal and makes permanent disability on the patient. Through this case, we demonstrate the potential of tooth infection which leads to septic CST and caused ophthalmoplegia and blindness.

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Cavernous Sinus Thrombosis and Blindness Complicating Dental Infection

Cited by 3 publications

References 14 publications

A case of aseptic bilateral cavernous sinus thrombosis following a recent inactivated SARS-CoV-2 vaccination

A case of aseptic bilateral cavernous sinus thrombosis following a recent inactivated SARS-CoV-2 vaccination

Serious Complications and Treatment Strategies Associated with Odontogenic Infections

Septic Cavernous Sinus Thrombosis (CST) with Blindness Caused by Odontogenic Infection – A Case Report

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