Cavity-based Chiral Polarimetry

Sofikitis, Dimitris; Katsoprinakis, G. E.; Spiliotis, Alexandros K.; Rakitzis, T. Peter

doi:10.1016/b978-0-444-64027-7.00018-5

Cited by 3 publications

(1 citation statement)

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“…In what follows, we describe two possible versions of ICOA explicitly; one designed to probe the optical rotation of a transparent sample regardless of the sample's linear birefringence (ICOA-OR) and another designed to probe gradients in the optical rotation of a transparent sample (ICOA-GOR). ICOA-OR and ICOA-GOR are distinct from all polarimetric techniques known to the authors at the time of writing, including HAUP-based techniques [7,10,11,13,14], existing polarization interferometry techniques [15], optical heterodyne polarimetry [16,17], Metripol-based techniques [7,18], CRDP and other such cavity-based techniques [19][20][21] and Mueller matrix polarimetry [9,22]. ICOA-GOR, in particular, has elements in common with, but is subtly distinct from, DIC-based techniques [23][24][25][26][27][28][29].…”

Section: Introductionmentioning

confidence: 99%

Interference-contrast optical activity: a new technique for probing the chirality of anisotropic samples and more

2020

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We introduce interference-contrast optical activity (ICOA) as a new technique for probing the chirality of anisotropic samples and more. ICOA could underpin a new class of ‘chiral microscopes’, with potential applications spanning the range of chirality and beyond. Two possible versions of ICOA are described explicitly; one designed to probe the optical rotation of a transparent sample regardless of the sample’s linear birefringence (ICOA-OR) and another designed to probe gradients in the optical rotation of a transparent sample (ICOA-GOR). Simulated results for α -quartz lead us to suggest that ICOA-GOR might be applied to help monitor the growth of chiral crystals in the pharmaceutical industry. Possible directions for future research are highlighted.

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Section: Introductionmentioning

confidence: 99%

Interference-contrast optical activity: a new technique for probing the chirality of anisotropic samples and more

2020

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Continuous-wave cavity ring-down polarimetry

Visschers

Tretiak

Budker

et al. 2020

The Journal of Chemical Physics

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We present a new cavity-based polarimetric scheme for highly sensitive and time-resolved measurements of birefringence and dichroism, linear and circular, that employs rapidly pulsed single-frequency continuous wave (CW) laser sources and extends current cavity-based spectropolarimetric techniques. We demonstrate how the use of a CW laser source allows for gains in spectral resolution, signal intensity, and data acquisition rate compared to traditional pulsed-based cavity ring-down polarimetry (CRDP). We discuss a particular CW-CRDP modality that is different from intensity-based cavity-enhanced polarimetric schemes as it relies on the determination of the polarization rotation frequency during a ring-down event generated by large intracavity polarization anisotropies. We present the principles of CW-CRDP and validate the applicability of this technique for the measurement of the non-resonant Faraday effect in solid SiO2 and CeF3 and gaseous butane. We give a general analysis of the fundamental sensitivity limits for CRDP techniques and show how the presented frequency-based methodology alleviates the requirement for high finesse cavities to achieve high polarimetric sensitivities and, thus, allows for the extension of cavity-based polarimetric schemes into different spectral regimes, but most importantly renders the CW-CRDP methodology particularly suitable for robust portable polarimetric instrumentations.

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On enhanced sensing of chiral molecules in optical cavities

Scott

Garcia-Santiago

Beutel

et al. 2020

Applied Physics Reviews

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The differential response of chiral molecules to incident left-and right-handed circularly polarized light is used for sensing the handedness of molecules. Currently, significant effort is directed toward enhancing weak differential signals from the molecules, with the goal of extending the capabilities of chiral spectrometers to lower molecular concentrations or small analyte volumes. Previously, optical cavities for enhancing vibrational circular dichroism have been introduced. Their enhancements are mediated by helicity-preserving cavity modes which maintain the handedness of light due to their degenerate TE and TM components. In this article, we simplify the design of the cavity and numerically compare it with the previous one using an improved model for the response of chiral molecules. We use parameters of molecular resonances to show that the cavities are capable of bringing the vibrational circular dichroism signal over the detection threshold of typical spectrometers for concentrations that are one to three orders of magnitude smaller than those needed without the cavities, for a fixed analyte volume. Frequency resolutions of current spectrometers result in enhancements of more than one order (two orders) of magnitude for the new (previous) design. With improved frequency resolution, the new design achieves enhancements of three orders of magnitude. We show that the TE/ TM degeneracy in perfectly helicity-preserving modes is lifted by factors that are inherent to the cavities. More surprisingly, this degeneracy is also lifted by the molecules themselves due to their lack of electromagnetic duality symmetry, that is, due to the partial change of helicity during the light-molecule interactions.

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Cavity-based Chiral Polarimetry

Cited by 3 publications

References 38 publications

Interference-contrast optical activity: a new technique for probing the chirality of anisotropic samples and more

Interference-contrast optical activity: a new technique for probing the chirality of anisotropic samples and more

Continuous-wave cavity ring-down polarimetry

On enhanced sensing of chiral molecules in optical cavities

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