The use of Chromated Copper Borate (CCB) for wood treatment is known with several studies on a laboratory scale. However, there is a lack of field studies to analyze the effect of the CCB over time. This study aimed to evaluate the wood properties of Eucalyptus urophylla S.T. Blake x Eucalyptus grandis W. Mill ex Maiden (called E. urograndis), treated with CCB as well evaluate the leaching of chromium, copper and bore (Cr/Cu/B) in field test. The field experiment, with wood treated and untreated (no CCB application), was installed in 2016 and remained until 2018. Wood physico-mechanical properties were evaluated for each condition (treated and untreated) and at three different time: at 0, 1 and 2 years of field exposure. The elements (Cr/Cu/B) losses (leaching) were determined by the difference in the quantification of each element retained in the wood (retention), from year 0 (amount of original elements) in relation to years 1 and 2 of field exposure. The preservative treatment of E. urograndis wood with CCB was efficient to maintain its physical and mechanical properties (mass loss, basic density, rupture and elasticity modulus) during the 2 years of field exposure. The E. urograndis wood without CCB treatment showed reductions in the physical-mechanical properties, indicating their low natural durability. High leaching (close to 100%) for boron was observed. In addition, the total of CCB retention has not changed (statistically) after 2 years.