CD26/dipeptidyl peptidase IV: A comparative study of healthy persons and kidney transplant recipients before and early after transplantation

Increased plasma dipeptidyl peptidase-4 activities are associated with high prevalence of diabetic nephropathy in Chinese patients with newly diagnosed type 2 diabetes: A cross-sectional study

“…In addition, as DN deteriorated, increased DPP4 activity might also occur as a result of reduced DPP4 clearance and decreased uptake and/or turnover by the cells of the reticular endothelial system. 30 Previous study 30 reported that DPP4 expression and soluble DPP4 concentration were significantly higher in subjects with end-stage kidney disease than in control subjects, and the DPP4 enzyme activity in these patients was also found to be higher. More importantly, DPP4 concentrations and its activities were found to be significantly decreased after kidney transplantation.…”

The perceptions of natural compounds against dipeptidyl peptidase 4 in diabetes: from in silico to in vivo

“…analyzed sDPP-4 activity in end-stage renal disease patients before and after kidney transplantation, and sDPP-4 activities were found to decrease after kidney transplantation. 50 These results suggest that serum sDPP-4 activity can be a potential biomarker for monitoring the progress of autoimmune disease and the prognosis of organ transplantation. Interestingly, serum sDPP-4 activity can be associated with the progress of chronic obstructive pulmonary disease (COPD), 51 which is highly correlated with respiratory inflammation, obviously indicating the relationship between serum sDPP-4 activity and COPD progression.…”

Lymphocyte surface molecules as immune activation biomarkers

“…Wieland and Shipkova, Lymphocyte surface molecules 14 sCD95) in the bloodstream have been investigated to a very limited extent [76][77][78]. As suggested for sCD30, the concentration of these soluble proteins has also been considered to serve as a surrogate marker for T cell activation [79], and if true, then this would be very attractive from both analytical (commercial kits available) and pre-analytical points of view (sample stability).…”