CD4+ T lymphocyte responses to viruses and virus-relevant stimuli in teleost fish

Bela-ong, Dennis Berbulla; Thompson, Kim D.; Kim, Hyoung Jun; Park, Seong Bin; Jung, Tae Sung

doi:10.1016/j.fsi.2023.109007

Cited by 4 publications

(1 citation statement)

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“…These cytokines can play important roles in stimulating the humoral immune system and provoking stronger antibody responses to viral antigens, demonstrating the cooperation between the cell-mediated and humoral arms of the immune system [49]. The use of antibodies specific to teleost CD4 have helped characterize T H cell responses to viral antigens in rainbow trout, zebrafish, and olive flounder (Paralichthys olivaceus), according to a recent review of T H cell responses [50], but continued development of these tools is necessary for a deeper understanding of T H cell function and response to various stimuli.…”

Section: Adaptive Immunitymentioning

confidence: 99%

An Introduction to Relevant Immunology Principles with Respect to Oral Vaccines in Aquaculture

Jones,

Cain

2023

Microorganisms

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Vaccines continue to play an enormous role in the progression of aquaculture industries worldwide. Though preventable diseases cause massive economic losses, injection-based vaccine delivery is cost-prohibitive or otherwise impractical for many producers. Most oral vaccines, which are much cheaper to administer, do not provide adequate protection relative to traditional injection or even immersion formulas. Research has focused on determining why there appears to be a lack of protection afforded by oral vaccines. Here, we review the basic immunological principles associated with oral vaccination before discussing the recent progress and current status of oral vaccine research. This knowledge is critical for the development and advancement of efficacious oral vaccines for the aquaculture industry.

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Section: Adaptive Immunitymentioning

confidence: 99%