2024
DOI: 10.3389/fimmu.2024.1387142
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CD8 T cells are dispensable for experimental autoimmune prostatitis induction and chronic pelvic pain development

Florencia C. Salazar,
Maria S. Martinez,
Daniela A. Paira
et al.

Abstract: IntroductionChronic Pelvic Pain Syndrome or Chronic Prostatitis (CPPS/CP) is the most prevalent urologic affliction among young adult men. It is a challenging condition to treat, which significantly decreases patient quality of life, mostly because of its still uncertain aetiology. In that regard, an autoimmune origin is a prominent supported theory. Indeed, studies in patients and in rodent models of Experimental Autoimmune Prostatitis (EAP) have provided compelling evidence suggesting a key role of CD4 Th1 c… Show more

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