Cecal gastrointestinal stromal tumor causing ileocolic intussusception in an adult: A rare case report

Abstract

Introduction and importance Cecal gastrointestinal stromal tumors (GIST) constitute a rarer subtype of all GISTs. Rarely, it can present with ileocolic intussusception in adults making it a challenging diagnosis due to non-specific clinical features. Case presentation A 30-year previously healthy woman presented with lower abdominal pain and a distended abdomen who was subsequently diagnosed with ileocolic intussusception on a CT scan. Intraoperatively, a pedunculated polypoid hard mass was identified in the cecum and thus, a standard right hemicolectomy was performed with the suspicion of malignancy. Histopathology of the resected mass confirmed CD117 negative, spindle type GIST. Discussion Cecal GIST presenting in the form of ileocolic intussusception is rare. Contrast-enhanced CT scan is the preferred imaging modality for the evaluation of patients with suspected GIST to determine the extent of the tumor, the presence or absence of metastatic disease alongside evaluation of the possibility of complete resection. Adjuvant imatinib therapy following complete resection decreases the disease recurrence. Conclusion Intussusception in an adult can be the first manifestation of underlying malignancy like GIST. Complete surgical resection of the tumor with a negative margin offers long-term survival.

Vomiting After Admission: Intussusception Due to Gastrointestinal Stromal Tumor (Gist)

“…Compared with males, females showed an increasing incidence rate of approximately 70%. The treatment of choice in these patients was complete surgical resection, as the use of laparotomy is very common (Hsieh et al, 2021; Shrestha et al, 2021).…”