Ceftriaxone-Induced Gallbladder Stones in Children

Abstract

Gallbladder stones in children is one complication that is mostly seen in diseases such as hemolytic diseases, liver disease, and obesity. It can also be a secondary complication of long-duration use of antibiotics like ceftriaxone. However, gallbladder stone, together with sludge themselves, is unusual within the children's population. We observed three children with gallbladder stones who were on along course of intravenous ceftriaxone. In this study, we present the three cases of children aged between eleven months to seven years who were treated with high doses and for an extended period (more than two weeks) of intravenous ceftriaxone for a complicated systemic bacterial infection. The goal of this study is to raise awareness about the possibility of developing gallbladder stones in pediatric patients who receive a long course of intravenous ceftriaxone.

Ceftriaxone-associated side effect findings in children’s abdominal ultrasonography

“…In our study 29.4% of the cases were symptomatic, referring right upper quadrant pain. There is no sex predominance in most studies (Ozturk et al, 2005;Araz et al, 2007;Heim-Duthoy et al, 1990;Al Saidi et al, 2021) while in our study females predominate over males in a 1.1:1 ratio. The symptoms in the symptomatic patients begun from 5 th -7 th day and last 20 days.…”