Celiac disease: how common is jejunoileal fold pattern reversal found at small-bowel follow-through?

Barlow, John M.; Johnson, C. Daniel; Stephens, DH

doi:10.2214/ajr.166.3.8623630

Cited by 20 publications

(12 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Jejunoileal fold pattern reversal, probably due to a compensatory effect of the ileum to the severe villous atrophy of the small bowel, is reported as a suggestive feature of CD [8,11]. It has also been reported that the reversal of the jejunoileal fold pattern is a common feature in barium studies, in patients with CD, and can be easily distinguished from the normal fold pattern [14].…”

Section: Discussionmentioning

confidence: 99%

Computed tomography of the small bowel in adult celiac disease: the jejunoileal fold pattern reversal

Tomei

Marini²,

Messineo³

et al. 2000

European Radiology

View full text Add to dashboard Cite

The aim of this retrospective study was to establish whether the distinctive intestinal fold pattern of celiac disease (CD), known by barium studies as jejunoileal fold pattern reversal (JFPR) may be recognized at CT. The number of intestinal folds per 2.5 cm, seen at CT, were counted in the jejunum and in the ileum of 22 adult patients with CD and compared with the folds of 30 consecutive subjects in whom an intestinal disease had been excluded. The results were submitted to statistical analysis by Student's t-test. In the control group the number of folds per 2.5 cm were 4.88 (SD +/- 0.78) in the jejunum and 2.84 ( +/- 0.62) in the ileum; in the CD group the number of folds were 2.42 ( +/- 1.61) in the jejunum and 5.11 ( +/- 1.24) in the ileum. There was a statistically significant difference in the number of jejunal and ileal folds between the CD patients and the control group (in both cases p < 0.001). The JFPR was seen in 15 patients with CD (68.2 %) but in none of the controls. Our study shows that JFPR is not a normal finding and can be demonstrated by CT in the majority of patients with CD.

show abstract

Section: Discussionmentioning

confidence: 99%

Computed tomography of the small bowel in adult celiac disease: the jejunoileal fold pattern reversal

Tomei

Marini²,

Messineo³

et al. 2000

European Radiology

View full text Add to dashboard Cite

show abstract

“…Herlinger and Maglinte [11] and Rubesin et al [12] reported the finding of equal or less than three folds per inch in the proximal jejunum, often referred to as "colonization" [13,15], to be highly suggestive of CD. In our study population this feature was present in 30% of patients with unknown and, subsequently biopsy-proven, celiac disease, but only in 1 patient (1%) of the control group who suffered from Crohn's disease.…”

Section: Discussionmentioning

confidence: 99%

“…In the proximal jejunum, less than four folds per inch were considered abnormal, and in the distal ileum, more than four folds per inch were considered abnormal [11,12]. The average number of folds per inch in the proximal jejunum and the distal ileum then were compared to demonstrate an eventual presence of jejunoileal fold pattern reversal, i.e., fewer folds per inch in the proximal jejunum compared with the distal ileum [13, 14,15].…”

Section: Image Analysismentioning

confidence: 99%

“…Various radiographic features of adult CD, including small bowel dilatation, flocculation of barium, and changes in the number and thickening of folds, have been previously described [11,12,13,14,15,16,17,18]. Nevertheless, few data are available about the diagnostic accuracy of the described features at enteroclysis in the detection of patients with CD.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Enteroclysis in adult celiac disease: diagnostic value of specific radiographic features

et al. 2003

View full text Add to dashboard Cite

“…Disorder with extensive compromise of the small bowel can be evaluated by a fluoroscopy based small bowel follow-through study. Thus, Barlow et al have recently shown that 86% of celiac disease patients can be detected by an abnormal fold pattern consisting of a decreased number of jejunal folds and an increased number of ileal folds (jejunoileal fold pattern reversal) [177]. However, these findings are highly controversial, especially taking into consideration that endoscopic biopsy is mandatory and the procedure is highly available and specific with notable advantages.…”

Section: Small Bowel Radiologymentioning

confidence: 99%

Malabsorption Syndromes

Bai¹

1998

Digestion

View full text Add to dashboard Cite

Background/Aims: Malabsorption syndromes commonly result from a pathological interference of the normal digestive process. There have been major advances in the last 4 years. The purpose of this review is to highlight in the form of a brief summary the most outstanding information available. Methods: The review was performed based on a medical literature search using MEDLINE (1993–1997), bibliographic reviews of book chapters and review articles. As a consequence of the extensive information incorporated in the period and the limited scope of this review, the review will focus in three aspects: (1) an overview on some clinical aspects of malabsorption; (2) diseases in which predominates the disturbed mucosal phase of the digestive process, and (3) providing information on diagnostic testing regarding malabsorption. Results: Major advances on celiac disease, Whipple’s disease, giardiasis, tropical sprue, malabsorption of oligo- and disaccharides, vitamin B₁₂ and bile salts are discussed. New aspects on diagnostic procedures for malabsorption are also presented. Conclusion: Although major advances have given a great support to the investigation of malabsorption, yet the syndrome remains a major diagnostic dilemma. Based on the limited availability of most diagnostic tests, a simple and practical diagnostic algorithm is presented.

show abstract

Celiac disease: how common is jejunoileal fold pattern reversal found at small-bowel follow-through?

Cited by 20 publications

References 4 publications

Computed tomography of the small bowel in adult celiac disease: the jejunoileal fold pattern reversal

Computed tomography of the small bowel in adult celiac disease: the jejunoileal fold pattern reversal

Enteroclysis in adult celiac disease: diagnostic value of specific radiographic features

Malabsorption Syndromes

Contact Info

Product

Resources

About