2021
DOI: 10.1142/s1793048021300024
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Cell Mechanics and Signalization: SARS-CoV-2 Hijacks Membrane Liquid Crystals and Cytoskeletal Fractal Topology

Abstract: We highlight changes to cell signaling under virus invasion (with the example of SARS-CoV-2), involving disturbance of membranes (plasma, mitochondrial, endothelial-alveolar) and of nanodomains, modulated by the cytoskeleton. Virus alters the mechanical properties of the membranes, impairing mesophase structures mediated by the fractal architecture initiated by actomyosin. It changes the topology of the membrane and its lipid composition distribution. Mechano-transduction, self-organization and topology far fr… Show more

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