Cell-Mediated Immunity in Two Species of Bats

Effects of Early Malnutrition on Mental System, Metabolic Syndrome, Immunity and the Gastrointestinal Tract

“…In rats, for example, malnutrition in dams caused impairment in the thymus [77]. Secondary to thymic atrophy, the production of thymic hormones that are critical for the differentiation of T lymphocytes was reduced, especially in protein-calorie malnutrition and zinc deficiency [49]. Rats from dams on a protein-deficient diet during gestation showed a permanent negative impact on growth and the size of organs including the thymus and spleen, even though they were given a wellbalanced diet after weaning [48].…”

Haematological alterations in protein malnutrition

“…The functional evaluation of T-cells by means of blastic response to mitogens, delayed hypersensitivity reactions, rejection to grafts and the production of lymphokines is variable. 66,92,[95][96][97][98][99] Thus, if on the one hand, we have a group of researchers reporting the occurrence of depression of the cellular response, 66,96,100 on the other we have studies whose results are the opposite, revealing that in protein malnutrition the cellular response becomes stimulated. 101,102 revisao -haematological alterations.p65 07/05/2004, 15: 48 52 As to the production of cytokines in states of malnutrition, there is also no consensus in literature.…”

Relationship between Vitamin C, Mast Cells and Inflammation

“…It is well known that the immune system is involved in cancer, infection, and allergy, as well as autoimmune and neurodegenerative diseases. Dietary supplementation with vitamin C, enhances a number of aspects of lymphocyte, macrophages and mast cell functions, exerts antiinflammatory effects in man and animals, and is an indicator of the degree of oxidative stress taking place in the plasma [11]. Moreover, high administration of vitamin C in experimental animals results in better outcome in sepsis, oxidative stress and inflammation [12].…”