2024
DOI: 10.1186/s12967-024-05900-6
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Cellular crosstalk in the bone marrow niche

Zeqi Huang,
Zoya Iqbal,
Zhe Zhao
et al.

Abstract: The bone marrow niche is a special microenvironment that comprises elements, including hematopoietic stem cells, osteoblasts, and endothelial cells, and helps maintain their characteristic functions. Here, we elaborate on the crosstalk between various cellular components, hematopoietic stem cells, and other cells in the bone marrow niche. We further explain the mechanism of preserving equilibrium in the bone marrow niche, which is crucial for the directional regulation of bone reconstruction and repair. Additi… Show more

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