Cellular, hemostatic, and inflammatory parameters of the surgical stress response in pigs undergoing partial pericardectomy via open thoracotomy or thoracoscopy

Abstract

Partial pericardectomy performed by thoracotomy or thoracoscopy in pigs produces a surgical stress response of equal magnitude, as measured by cellular, hemostatic, and inflammatory changes.

Impact of retransfusion of blood processed in cell-saver on coagulation versus cardiopulmonary bypass: A prospective observational study using thromboelastography

“…In case of surgery in which massive blood loss is expected or can be sudden, a machine for recuperation of blood -a cell-saver is advocated 4 . Cell-saver machines enable processing the blood removed by suction and to return it to the patient's circulation despite impact on coagulation 5,6 . The filters of cell-savers can remove large particles as fat or tissue but cannot delete tissue factor and other cytokines released due to surgical trauma and affecting coagulation 7 .…”

Comparison of early stage electrocardiographic, echocardiographic and histopathologic results of partial pericardiectomy and thoracoscopic pericardial window techniques in an animal model

“…disturbance, shock, oliguria and prolonged anesthesia time (Jackson et al, 1999) thoracoscopy is preferred to manage pericardial disease and effusions (Jackson et al, 1999;Palsgaard et al, 2007;Bicer et al, 2015). Considering this and previous postoperative clinical results, comparative investigation of the partial pericardiectomy through thoracotomy and thoracoscopic pericardial window techniques was planned in an experimental animal model.…”

“…The presenting malignant, infectious or idiopathic etiologies may indicate the need for pericardiectomy in small animals (Dupre et al, 2001;Case, 2016). The objective of pericardiectomy is to excise sufficient pericardium to excise enough pericardium to eliminate tamponade and to obtain a histologic diagnosis of the patient's condition (Palsgaard et al, 2007;Case, 2016). For this purpose, partial and total pericardiectomy are described, and these techniques are performed via a lateral thoracotomy, median sternotomy or thoracoscopic approach (Hardy et al, 1992;Jackson et al, 1999;Dupre et al, 2001;Palsgaard et al, 2007;Vistarini et al, 2015;Case, 2016).…”

“…The objective of pericardiectomy is to excise sufficient pericardium to excise enough pericardium to eliminate tamponade and to obtain a histologic diagnosis of the patient's condition (Palsgaard et al, 2007;Case, 2016). For this purpose, partial and total pericardiectomy are described, and these techniques are performed via a lateral thoracotomy, median sternotomy or thoracoscopic approach (Hardy et al, 1992;Jackson et al, 1999;Dupre et al, 2001;Palsgaard et al, 2007;Vistarini et al, 2015;Case, 2016). Partial pericardiectomy is a valuable treatment for cases with constrictive pericarditis because echocardiographic symptoms of this constriction (progressive fluid overload, reduced cardiac output and right ventricular pressure disturbance) are only terminated by pericardial surgery (Hardy et al, 1992;Bicer et al, 2015;Busch et al, 2015;Vistarini et al, 2015).…”

“…Partial pericardiectomy is a valuable treatment for cases with constrictive pericarditis because echocardiographic symptoms of this constriction (progressive fluid overload, reduced cardiac output and right ventricular pressure disturbance) are only terminated by pericardial surgery (Hardy et al, 1992;Bicer et al, 2015;Busch et al, 2015;Vistarini et al, 2015). Thoracoscopic surgery, compared to the open thoracic approach, decreases surgical stress, pain and postoperative complications; as a result, it is recommended as a minimally invasive technique for treating some pericardial diseases in veterinary practice (Dupre et al, 2016;Palsgaard et al, 2007;Case, 2016). In humans, partial pericardiectomy increases the survival time, relieves the clinical symptoms and prevents a second disease from worsening the health status of the patient (Vistarini et al, 2015).…”