Cellular Processes Caused by Human Herpesviruses Infection

Abstract

Herpesvirus is a prevalent pathogen that primarily infects human epithelial cells and has the ability to reside in neurons. In the field of otolaryngology, herpesvirus infection primarily leads to hearing loss and vestibular neuritis, and is considered the primary hypothesis regarding the pathogenesis of vestibular neuritis. Individuals afflicted with vestibular neuritis experience diz-ziness, which significantly impacts their daily lives. The impact of herpes virus infection on host cell processes and the targeted clearance of infected host cells by immune cells are likely the primary pathogenic mechanisms underlying vestibular neuritis. In this review, we provide a summary of the effects of herpes virus on cellular processes in both host cells and immune cells, with a focus on HSV-1 and HCMV as illustrative examples.