Cellular Spindled Histiocytic Pseudotumor: A Benign Mimic of Spindle Cell Neoplasia of the Breast

East, Ellen G.; Carter, Cody S.; Sciallis, Andrew P.

doi:10.5858/arpa.2019-0421-ra

Cited by 3 publications

(1 citation statement)

References 25 publications

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“…IPT-FDCS is a unique tumor associated with EBV infection, as opposed to other inflammatory pseudotumors (IPTs). The concept of IPTs was first described in 1903 and encompassed various conditions, including infective, autoimmune, or reactive fibroinflammatory processes [74][75][76][77][78]. Inflammatory myofibroblastic tumors (IMTs), on the other hand, were distinguished from this heterogeneous group of IPTs and are classified as intermediate-grade neoplasms, largely due to the identification of recurrent gene rearrangements [78].…”

Section: Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcomamentioning

confidence: 99%

A Clinicopathology Review and Update of Epstein–Barr Virus-Associated Mesenchymal Tumors

Lee,

Omar,

Tay

et al. 2023

Cancers

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The Epstein–Barr virus (EBV) is associated with various tumor types, including nasopharyngeal carcinoma and lymphoproliferative disorders. While much is known about EBV-related epithelial and lymphoid tumors, there is a paucity of knowledge concerning EBV-associated mesenchymal tumors. This review aims to provide a comprehensive overview of EBV-associated mesenchymal tumors, encompassing their clinical features, pathological characteristics, pathophysiology, prognostic factors, and current treatment approaches. Through an extensive literature search using the PubMed database, we were able to identify three distinct EBV-associated mesenchymal tumors: EBV-associated smooth muscle tumors, inflammatory pseudotumor-like follicular dendritic cell sarcomas, and EBV-associated osteosarcomas. Although this review extensively explored the different aspects of these mesenchymal tumors, our comprehension of the underlying pathophysiology in this context is still incomplete. Therefore, we hope that this review paper will not only serve as a valuable repository of information but also serve as a catalyst for prospective in vitro and in vivo research studies to bridge the existing knowledge gap surrounding pathophysiology, ultimately making an important contribution to shaping future therapeutic approaches.

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Section: Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcomamentioning

confidence: 99%

A Clinicopathology Review and Update of Epstein–Barr Virus-Associated Mesenchymal Tumors

Lee,

Omar,

Tay

et al. 2023

Cancers

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Mesenchymal Breast Tumors with Fibroblastic and Myofibroblastic Differentiation

Weisman

Buehler

2021

Mesenchymal Tumors of the Breast and Their Mimics

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Inflammatory Lesions of the Breast

Turashvili

2023

Archives of Pathology &Amp; Laboratory Medicine

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Context.— Inflammatory lesions of the breast are rare but not infrequently pose problems both clinically and morphologically, particularly on needle core biopsies. These lesions range from acute inflammatory conditions to chronic lymphoplasmacytic and lymphohistiocytic to granulomatous inflammatory diseases. Objective.— To provide a comprehensive overview of inflammatory lesions of the breast with etiopathogenesis and clinical, radiologic, and pathologic features, with differential diagnostic considerations, clinical management, and prognosis. Data Sources.— The existing literature in the English language, including original research articles and review articles describing inflammatory lesions of the breast. Conclusions.— Inflammatory lesions of the breast are characterized by a wide variety of clinical, radiologic, and morphologic features. The histopathologic differential diagnosis often includes a neoplastic process requiring ancillary studies and correlation with clinical and radiologic findings. Although most specimens display nonspecific findings precluding a definitive pathologic diagnosis, pathologists have a unique opportunity to play a crucial role in identifying key histologic features suggestive of certain entities, such as cystic neutrophilic granulomatous mastitis, immunoglobulin (Ig) G4 mastitis, or squamous metaplasia of lactiferous ducts, in the right clinical and radiologic context, and thereby guiding optimal and timely clinical management. The information presented herein will be helpful to practicing anatomic pathologists and pathology trainees in becoming more familiar with specific morphologic features and overcoming differential diagnostic challenges related to pathology reporting of inflammatory lesions of the breast.

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Cellular Spindled Histiocytic Pseudotumor: A Benign Mimic of Spindle Cell Neoplasia of the Breast

Cited by 3 publications

References 25 publications

A Clinicopathology Review and Update of Epstein–Barr Virus-Associated Mesenchymal Tumors

A Clinicopathology Review and Update of Epstein–Barr Virus-Associated Mesenchymal Tumors

Mesenchymal Breast Tumors with Fibroblastic and Myofibroblastic Differentiation

Inflammatory Lesions of the Breast

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