Cellular Therapy as Promising Choice of Treatment for COVID-19

Abstract

In the pandemic of COVID-19, while living normals have been changing, there have been a huge effort globally to find out effective and safe treatment agents and vaccines. As of now, the advances show the progress in vaccine development, however the treatment of the COVID-19 is yet not fully specified. The drugs, i.e. antibiotics, antivirals, antimalarians, even anti-HIV agents which have been known already were taken out of the shelves and brought into use in different combinations. On the other hand, the cellular treatment, more specifically the mesenchymal stem cell therapy has been encouraged, resulting in various evidence published all over the world. This chapter aims to compile the published information, in means of methods, disease manifestations, results and limitations, about the stem cell treatment of the COVID-19 and to provide a source of harmonized reference for scientific society.

The therapeutic potential of mesenchymal stem cells in COVID-19: Present and future

“…Studies have also shown improvement in lung function after MSC therapy (Feng et al 2020;Feng et al 2021;Monsel et al 2022). In addition to having immunomodulatory properties to suppress injury due to immune reactions, MSCs can also suppress ARDS exacerbations, repair damaged tissue, and inhibit pulmonary fibrosis (Irmak and Karaoz 2021). MSCs enter the body through the intravenous route and are concentrated in the lungs.…”