2018
DOI: 10.5114/ada.2018.77235
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Cellulite: a cosmetic or systemic issue? Contemporary views on the etiopathogenesis of cellulite

Abstract: Cellulite (also known as gynoid lipodystrophy or orange peel syndrome) is one of the most common lipodystrophy syndromes, which affects millions of post-adolescent women. Cellulite is manifested by topographic disorders of subcutaneous tissue such as nodules, edema, and abnormal fibrosis. It is located mainly on the pelvic area, especially on the buttocks. Its pathogenesis is complexed and unclear. There are several theories about its pathophysiology. Hormonal disorders, endothelial dysfunction and genetic pre… Show more

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Cited by 49 publications
(85 citation statements)
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“…Most postadolescent women have cellulite [ 65 , 66 ]. Cellulite is manifested by topographic disorders of subcutaneous tissue, such as nodules, edema, and abnormal fibrosis [ 67 ].…”
Section: Cosmetic Propertiesmentioning
confidence: 99%
“…Most postadolescent women have cellulite [ 65 , 66 ]. Cellulite is manifested by topographic disorders of subcutaneous tissue, such as nodules, edema, and abnormal fibrosis [ 67 ].…”
Section: Cosmetic Propertiesmentioning
confidence: 99%
“…Lipodystrofia gynoidalna stanowi w obecnych czasach bardzo szeroki problem. Szacuje się, że dotyka od 80 do 90% kobiet w wieku postpokwitaniowym [16,17]. Jak już wspomniano, istnieje wiele metod stosowanych w zmniejszaniu widoczności tego defektu kosmetycznego.…”
Section: Dyskusjaunclassified
“…Skóra objęta zmianami cellulitowymi jest często sucha, ma zmieniony koloryt, a w nasilonym stadium lipodystrofii może dawać odczucia bólowe [17]. Działania niwelujące objawy cellulitu powinny także poprawiać podstawowe cechy skóry, takie jak poziom nawilżenia, jej funkcja barierowa i pH.…”
Section: Dyskusjaunclassified
“…Gynoidal fat is regarded as an attractive feature in women but when excessive, it is perceived as ugly. It is associated with excessive fat accumulation in these deposits but its etiology is subject to several theories [ 1 ]. Most highlight superficial fat, especially gynoidal fat promoted by estradiol via its estrogen receptor alpha (ERa) while fat cells produce estrogen, particularly in obesity.…”
Section: Introductionmentioning
confidence: 99%