“…Dextran, a glucose derived natural biodegradable polysaccharide, has been extensively utilised to create a range of antimicrobial materials. 283–285 An investigation conducted by Tuchilus et al used dextran (Either 8000 or 4500 average molar masses) as a backbone to create a self-assembling amphiphile achieving potent antimicrobial activity against MRSA. 286 In this study quaternary pendant ammonium groups were attached to the dextran backbones, while varied length alkyl chains were incorporated at the reductive end of the polysaccharide, producing a series of dextran derivatives, 48–55 (Fig.…”