Centrifugal air-assisted melt agglomeration for fast-release “granulet” design

Melt pelletization of alginate: Effects of air pressurization on consolidation and drug release property of pellets

“…Commonly, the density of a matrix is manipulated through varying the magnitude of agitation forces (Bukovec et al, 2009). Recently, a new dosage form concept known as "granulets", where round agglomerates with porous core are produced for use as fast-release drug delivery system, has been developed (Wong and Musa, 2012). In such case, centrifugal shear-free moving air stream is utilized as a replacement of impeller blade to agitate processing materials.…”